Evidence map›Paper›PMID 26825684›Full record

ArticleJournal of the American Medical Directors Association2016

Walking-Induced Fatigue Leads to Increased Falls Risk in Older Adults.

Steven Morrison, Sheri R Colberg, Henri K Parson, Serina Neumann, Richard Handel, Etta J Vinik, James Paulson, Arthur I Vinik

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
12.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Versatile Exoskeleton Control Supports Elderly Joint Energetics During Hip-Intensive Tasks.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026
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  7. Article
  8. Review
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  10. Article
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  13. The effect of exercise-induced muscle fatigue on gait parameters among older adults: a systematic review and meta-analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Analyzing population-level trials as N-of-1 trials: An application to gait.Contemporary clinical trials communications · 2024
    Article
  18. Article
  19. The effect of prolonged walking on leg muscle activity patterns and vulnerability to perturbations.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Steven MorrisonSchool of Physical Therapy and Athletic Training, Old Dominion University, Norfolk, VA. Electronic address: smorriso@odu.edu.
Sheri R ColbergHuman Movement Sciences Department, Old Dominion University, Norfolk, VA.
Henri K ParsonStrelitz Diabetes Center, Eastern Virginia Medical School, Norfolk, VA.
Serina NeumannDepartment of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School, Norfolk, VA.
Richard HandelDepartment of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School, Norfolk, VA.
Etta J VinikStrelitz Diabetes Center, Eastern Virginia Medical School, Norfolk, VA.
James PaulsonPsychology Sciences Department, Old Dominion University, Norfolk, VA.
Arthur I VinikStrelitz Diabetes Center, Eastern Virginia Medical School, Norfolk, VA.
Eastern Virginia Medical School · USOld Dominion University · US

Funding

Quality of Life Tool Sensitive to Cognitive and Physical Measures of FatigueR21AG037123 · NIA · EASTERN VIRGINIA MEDICAL SCHOOL · PI VINIK, AARON I. · 2011 to 2012
$333k
NIA NIH HHS R21 AG037123
6 · The paper itself

Abstract

backgroundFor older adults, falls are a serious health problem, with more than 30% of people older than 65 suffering a fall at least once a year. One element often overlooked in the assessment of falls is whether a person's balance, walking ability, and overall falls risk is affected by performing activities of daily living such as walking.

objectiveThis study assessed the immediate impact of incline walking at a moderate pace on falls risk, leg strength, reaction time, gait, and balance in 75 healthy adults from 30 to 79 years of age. Subjects were subdivided into 5 equal groups based on their age (group 1, 30-39 years; group 2, 40-49 years; group 3, 50-59 years; group 4, 60-69 years; group 5, 70-79 years).

methodsEach person's falls risk (using the Physiological Profile Assessment), simple reaction time, leg strength, walking ability, and standing balance were assessed before and after a period of incline walking on an automated treadmill. The walking task consisted of three 5-minute trials at a faster than preferred pace. Fatigue during walking was elicited by increasing the treadmill incline in increments of 2° (from level) every minute to a maximum of 8°.

resultsAs predicted, significant age-related differences were observed before the walking activity. In general, increasing age was associated with declines in gait speed, lower limb strength, slower reaction times, and increases in overall falls risk. Following the treadmill task, older adults exhibited increased sway (path length 60-69 years; 10.2 ± 0.7 to 12.1 ± 0.7 cm: 70-79 years; 12.8 ± 1.1 to 15.1 ± 0.8 cm), slower reaction times (70-79 years; 256 ± 6 to 287 ± 8 ms), and declines in lower limb strength (60-69 years; 36 ± 2 to 31 ± 1 kg: 70-79 years; 32.3 ± 2 to 27 ± 1 kg). However, a significant increase in overall falls risk (pre; 0.51 ± 0.17: post; 1.01 ± 0.18) was only seen in the oldest group (70-79 years). For all other persons (30-69 years), changes resulting from the treadmill-walking task did not lead to a significant increase in falls risk.

conclusionsAs most falls occur when an individual is moving and/or fatigued, assessing functional properties related to balance, gait, strength, and falls risk in older adults both at rest and following activity may provide additional insight.

Indexed as

FatigueAccidental FallsAdultAgedExercise TestHumansMiddle AgedPostural BalanceReaction TimeRisk AssessmentWalkingagebalancefallsFatiguegait

Identifiers

PMID26825684
PMCPMC4842152
OpenAlexW2262526854

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.