ArticleJournal of the American Medical Directors Association2016
Walking-Induced Fatigue Leads to Increased Falls Risk in Older Adults.
Article in Journal of the American Medical Directors Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Effects of experimentally induced fatigue on healthy older adults' gait: A systematic review.PloS one · 2019Pooled it
- Trial
- Development of a Wearable Sensor Platform for Fall Risk Assessment and Fall Detection.Sensors (Basel, Switzerland) · 2026Article
- Sex-specific effects of fatiguing exercise on skeletal muscle passive mechanics are preserved in aging.bioRxiv : the preprint server for biology · 2026Article
- Discriminating Between Fallers and Non-Fallers Using Kinematic Data from the Heel2Toe™ Wearable Sensor.Sensors (Basel, Switzerland) · 2026Article
- Versatile Exoskeleton Control Supports Elderly Joint Energetics During Hip-Intensive Tasks.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Non-local Muscle Fatigue in Young and Middle-Aged Women following Fast-Paced Walking.International journal of exercise science · 2026Article
- The effects of aerobic exercise on sleep quality in older adults with sleep problems: a systematic review and meta-analysis of randomized controlled trials.Frontiers in psychology · 2026Review
- How does age affect changes in leg muscle activation patterns and leg joint moments during prolonged walking?European journal of applied physiology · 2025Article
- The effects of hip abductor fatigue on gait instability in older adults.Journal of neurophysiology · 2025Article
- Characteristics of Post-Exercise Lower Limb Muscle Tremor Among Speed Skaters.Sensors (Basel, Switzerland) · 2025Article
- Gait Characteristics Related to Fatigue in Patients With Type 2 Diabetes: Cross-Sectional Study.Cureus · 2025Article
- The effect of exercise-induced muscle fatigue on gait parameters among older adults: a systematic review and meta-analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025Review
- Effectiveness of Using a Digital Wearable Plantar Pressure Device to Detect Muscle Fatigue: Within-Subject, Repeated Measures Experimental Design.JMIR human factors · 2025Article
- Fatiguing exercise reduces cellular passive Young's modulus in human vastus lateralis muscle.Experimental physiology · 2024Article
- Correlation between postural stability and fall risk in trans-femoral amputees due to muscle fatigue.Journal of physical therapy science · 2024Article
- Analyzing population-level trials as N-of-1 trials: An application to gait.Contemporary clinical trials communications · 2024Article
- Blood flow restricted walking: does the hypoxic environment compromise walking technique?Frontiers in sports and active living · 2024Article
- The effect of prolonged walking on leg muscle activity patterns and vulnerability to perturbations.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2023Article
- Exploring the role of the left DLPFC in fatigue during unresisted rhythmic movements.Psychophysiology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundFor older adults, falls are a serious health problem, with more than 30% of people older than 65 suffering a fall at least once a year. One element often overlooked in the assessment of falls is whether a person's balance, walking ability, and overall falls risk is affected by performing activities of daily living such as walking.
objectiveThis study assessed the immediate impact of incline walking at a moderate pace on falls risk, leg strength, reaction time, gait, and balance in 75 healthy adults from 30 to 79 years of age. Subjects were subdivided into 5 equal groups based on their age (group 1, 30-39 years; group 2, 40-49 years; group 3, 50-59 years; group 4, 60-69 years; group 5, 70-79 years).
methodsEach person's falls risk (using the Physiological Profile Assessment), simple reaction time, leg strength, walking ability, and standing balance were assessed before and after a period of incline walking on an automated treadmill. The walking task consisted of three 5-minute trials at a faster than preferred pace. Fatigue during walking was elicited by increasing the treadmill incline in increments of 2° (from level) every minute to a maximum of 8°.
resultsAs predicted, significant age-related differences were observed before the walking activity. In general, increasing age was associated with declines in gait speed, lower limb strength, slower reaction times, and increases in overall falls risk. Following the treadmill task, older adults exhibited increased sway (path length 60-69 years; 10.2 ± 0.7 to 12.1 ± 0.7 cm: 70-79 years; 12.8 ± 1.1 to 15.1 ± 0.8 cm), slower reaction times (70-79 years; 256 ± 6 to 287 ± 8 ms), and declines in lower limb strength (60-69 years; 36 ± 2 to 31 ± 1 kg: 70-79 years; 32.3 ± 2 to 27 ± 1 kg). However, a significant increase in overall falls risk (pre; 0.51 ± 0.17: post; 1.01 ± 0.18) was only seen in the oldest group (70-79 years). For all other persons (30-69 years), changes resulting from the treadmill-walking task did not lead to a significant increase in falls risk.
conclusionsAs most falls occur when an individual is moving and/or fatigued, assessing functional properties related to balance, gait, strength, and falls risk in older adults both at rest and following activity may provide additional insight.
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Registered trials
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