Evidence map›Paper›PMID 26825403›Full record

ArticleFemale pelvic medicine & reconstructive surgery

Effect of Scopolamine Patch Use on Postoperative Voiding Function After Transobturator Slings.

Sybil G Dessie, Michele R Hacker, Costas Apostolis, Ellen O Boundy, Anna M Modest, Stephanie-Marie L Jones, Peter L Rosenblatt

Open access · greenAbstract read
In one paragraph

Article in Female pelvic medicine & reconstructive surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sybil G DessieFrom the *Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center; †Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston; and ‡Department of Obstetrics and Gynecology, Mount Auburn Hospital, Cambridge, MA.
Michele R Hacker
Costas Apostolis
Ellen O Boundy
Anna M Modest
Stephanie-Marie L Jones
Peter L Rosenblatt
Mount Auburn Hospital · USBeth Israel Deaconess Medical Center · US

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
NCATS NIH HHS UL1 TR001102NCRR NIH HHS UL1 RR025758
6 · The paper itself

Abstract

objectivesThe aim of this study was to determine whether the use of a preoperative transdermal scopolamine (TDS) patch for postoperative nausea and vomiting prophylaxis affects the success of a voiding trial after a transobturator tape sling procedure.

methodsThis study is a retrospective cohort study of adult women who underwent a transobturator tape sling procedure without concomitant procedures from February 1, 2009 through August 1, 2010. The exposed group included all eligible women who received a preoperative TDS patch. For each exposed woman, we selected the next 2 consecutive eligible women who did not receive a TDS patch to be included in the unexposed group. The primary outcome was postoperative voiding trial failure.

resultsWe identified 35 women who met eligibility criteria and used a preoperative TDS patch, and included 70 women who did not use a preoperative TDS. A significantly higher proportion of women in the TDS patch group (54.3%) failed their voiding trial than in the group that did not receive TDS (7.1%, P ≤ 0.001). A history of an incontinence procedure, older age, and higher body mass index strengthened the association between TDS patch and voiding trial failure. The adjusted model yielded a risk ratio for voiding trial failure of 13.8 (95% confidence interval, 5.2-36.5) for women who received TDS patch compared with those who did not.

conclusionsThe results of this study demonstrate that use of TDS patches for postoperative nausea and vomiting prophylaxis may negatively affect the success of voiding trials after transobturator tape sling procedures.

Indexed as

Administration, CutaneousAdultCase-Control StudiesFemaleHumansMiddle AgedMuscarinic AntagonistsPostoperative Nausea and VomitingPostoperative PeriodPreoperative PeriodRetrospective StudiesScopolamineSuburethral SlingsUrinary BladderUrinary Incontinence, StressUrinationMuscarinic AntagonistsScopolamine

Identifiers

PMID26825403
PMCPMC4846570
OpenAlexW2315182877

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.