Evidence map›Paper›PMID 26825151›Full record

ArticleAnesthesiology2016

Preoperative Laboratory Investigations: Rates and Variability Prior to Low-risk Surgical Procedures.

Kyle R Kirkham, Duminda N Wijeysundera, Ciara Pendrith, Ryan Ng, Jack V Tu, Andrew S Boozary, Joshua Tepper, Michael J Schull, Wendy Levinson, R Sacha Bhatia

Abstract read
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In one paragraph

Article in Anesthesiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Inappropriate use of clinical practices in Canada: a systematic review.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Pooled it
  2. Association between model of anesthesiology care and outcomes after cataract surgery: a population-based cohort study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Kyle R KirkhamFrom the Department of Anesthesia and Pain Management, Toronto Western Hospital, Toronto, Ontario, Canada (K.R.K.); Department of Anesthesia, Women's College Hospital, Toronto, Ontario, Canada (K.R.K.); Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada (D.N.W.); Department of Anesthesia and Pain Management, Toronto General Hospital, Toronto, Ontario, Canada (D.N.W.); Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada (D.N.W., J.V.T., J.T., M.J.S., R.S.B.); Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada (D.N.W., R.N., J.V.T., M.J.S., R.S.B.); Institute for Health System Solutions, Women's College Hospital, Toronto, Ontario, Canada (C.P., R.S.B.); Department of Medicine, University of Toronto, Toronto, Ontario, Canada (J.V.T., M.J.S., W.L., R.S.B.); Division of Cardiology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (J.V.T.); Department of Health Policy and Management, Harvard School of Public Health, Boston, Massachusetts (A.S.B.); Health Quality Ontario, Toronto, Ontario, Canada (J.T.); Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada (J.T.); Department of Emergency Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (M.J.S.); and Department of Cardiology, Women's College Hospital, Toronto, Ontario, Canada (R.S.B.).
Duminda N Wijeysundera
Ciara Pendrith
Ryan Ng
Jack V Tu
Andrew S Boozary
Joshua Tepper
Michael J Schull
Wendy Levinson
R Sacha Bhatia

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

backgroundIncreasing attention has been focused on low-value healthcare services. Through Choosing Wisely campaigns, routine laboratory testing before low-risk surgery has been discouraged in the absence of clinical indications. The authors investigated rates, determinants, and institutional variation in laboratory testing before low-risk procedures.

methodsPatients who underwent ophthalmologic surgeries or predefined low-risk surgeries in Ontario, Canada, between April 1, 2008, and March 31, 2013, were identified from population-based administrative databases. Preoperative blood work was defined as a complete blood count, prothrombin time, partial thromboplastin, or basic metabolic panel within 60 days before an index procedure. Adjusted associations between patient and institutional factors and preoperative testing were assessed with hierarchical multivariable logistic regression. Institutional variation was characterized using the median odds ratio.

resultsThe cohort included 906,902 patients who underwent 1,330,466 procedures (57.1% ophthalmologic and 42.9% low-risk surgery) at 119 institutions. Preoperative blood work preceded 400,058 (30.1%) procedures. The unadjusted institutional rate of preoperative blood work varied widely (0.0 to 98.1%). In regression modeling, significant predictors of preoperative testing included atrial fibrillation (adjusted odds ratio [AOR], 2.58; 95% CI, 2.51 to 2.66), preoperative medical consultation (AOR, 1.68; 95% CI, 1.65 to 1.71), previous mitral valve replacement (AOR, 2.33; 95% CI, 2.10 to 2.58), and liver disease (AOR, 1.69; 95% CI, 1.55 to 1.84). The median odds ratio for interinstitutional variation was 2.43.

conclusionsResults of this study suggest that testing is associated with a range of clinical covariates. However, an association was similarly identified with preoperative consultation, and significant variation between institutions exists across the jurisdiction.

Indexed as

Surgical Procedures, OperativeAdolescentAdultAgedAged, 80 and overClinical Laboratory TechniquesCohort StudiesFemaleHumansMaleMiddle AgedOdds RatioOntarioPreoperative CareRetrospective StudiesRisk

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.