Evidence map›Paper›PMID 26825045›Full record

ArticlePediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2016

Strategies to Maximize Enrollment in a Prospective Study of Comatose Children in the PICU.

Kristin L McBain, Eric T Payne, Rohit Sharma, Helena Frndova, Nicholas S Abend, Sarah M Sánchez, William B Gallentine, Karen M Cornett, Kendall B Nash, O Carter Snead and 3 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Kristin L McBain1Division of Neurology, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada. 2Department of Critical Care Medicine, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada. 3Division of Pediatric Neurology, Department of Neurology, Mayo Clinic, Rochester, MN. 4Departments of Neurology and Pediatrics, The Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. 5Division of Neurology, Department of Pediatrics, Duke Children's Hospital and Duke University School of Medicine, Durham, NC. 6Department of Neurology, University of California San Francisco, San Francisco, CA.
Eric T Payne
Rohit Sharma
Helena Frndova
Nicholas S Abend
Sarah M Sánchez
William B Gallentine
Karen M Cornett
Kendall B Nash
O Carter Snead
Christopher S Parshuram
Jamie S Hutchison
Cecil D Hahn
Apple (Israel) · ILUniversity of Toronto · CA

Funding

Non-convulsive seizures in critically ill children:physiology and outcomeK23NS076550 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI ABEND, NICHOLAS SCOTT · 2011 to 2015
$877k
Canadian Institutes of Health Research NI10-021NINDS NIH HHS K23 NS076550NINDS NIH HHS K23NS076550
6 · The paper itself

Abstract

objectivesTo analyze barriers to recruitment encountered during a prospective study in the PICU and evaluate strategies implemented to improve recruitment.

designProspective observational study of continuous electroencephalogram monitoring in comatose children.

settingPICUs at four North American institutions. PATIENTS: Patients with a Glasgow Coma Scale score of less than or equal to 8 for at least an hour.

interventionsFour strategies to increase recruitment were sequentially implemented. MEASUREMENTS AND MAIN

resultsThe baseline enrollment rate was 2.1 subjects/mo, which increased following the single-site introduction of real-time patient screening using an online dashboard (4.5 subjects/mo), deferred consenting (5.2 subjects/mo), and weekend screening (6.1 subjects/mo). However, the subsequent addition of three new study sites was the greatest accelerator of enrollment (21 subjects/mo), representing a 10-fold increase from baseline (p < 0.0001).

conclusionsIdentifying barriers to recruitment and implementing creative strategies to increase recruitment can successfully increase enrollment rates in the challenging ICU environment.

Indexed as

ComaIntensive Care Units, PediatricPatient SelectionChildElectroencephalographyGlasgow Coma ScaleHumansObservational Studies as TopicProspective Studies

Identifiers

PMID26825045
PMCPMC4779671
OpenAlexW2316164208

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.