Evidence map›Paper›PMID 26824946›Full record

ArticleAntimicrobial agents and chemotherapy2016

Is Aerosolized Pentamidine for Pneumocystis Pneumonia Prophylaxis in Renal Transplant Recipients Not as Safe as We Might Think?

N Macesic, K Urbancic, F Ierino, M L Grayson

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Taking the challenge: A protocolized approach to optimize Pneumocystis pneumonia prophylaxis in renal transplant recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

N MacesicDepartment of Infectious Diseases, Austin Health, Melbourne, Australia Division of Infectious Diseases, Columbia University Medical Center, New York, New York, USA nenad.macesic@austin.org.au lindsay.grayson@austin.org.au.
K UrbancicDepartment of Infectious Diseases, Austin Health, Melbourne, Australia.
F IerinoDepartment of Nephrology, Austin Health, Melbourne, Australia Department of Medicine, University of Melbourne, Melbourne, Australia.
M L GraysonDepartment of Infectious Diseases, Austin Health, Melbourne, Australia Department of Medicine, University of Melbourne, Melbourne, Australia nenad.macesic@austin.org.au lindsay.grayson@austin.org.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outbreaks ofPneumocystispneumonia have been described in renal transplant recipients. Aerosolized pentamidine is frequently used for prophylaxis in this setting. We report our experience with aerosolized pentamidine use in 56 renal transplant recipients. We found high rates of adverse reactions in patients with chronic respiratory disease.

Indexed as

Kidney TransplantationAdultAerosolsAntifungal AgentsBronchial SpasmFemaleHumansLungMalePentamidinePneumocystisPneumonia, PneumocystisRenal Insufficiency, ChronicRespiratory Tract DiseasesTransplant RecipientsTrimethoprim, Sulfamethoxazole Drug CombinationAerosolsAntifungal AgentsPentamidineTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID26824946
PMCPMC4808234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.