ArticleActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2015
Differential diagnosis of parotid gland tumours: which magnetic resonance findings should be taken in account?
Article in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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25 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Radiological features of head and neck mammary analogue secretory carcinoma: 11 new cases with a systematic review of 29 cases reported in 28 publications.Neuroradiology · 2021Pooled it
- Quantitative Permeability MRI for Preoperative Differentiation of Warthin Tumors and Malignant Salivary Gland Lesions.Diagnostics (Basel, Switzerland) · 2026Article
- Importance of magnetic resonance in the diagnosis of pleomorphic parotid adenoma. Clinical case series.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Advanced magnetic resonance neurography for preoperative facial nerve assessment and surgical planning in parotid tumors: a review of current evidence and surgical translation.Frontiers in oncology · 2026Review
- Using Machine Learning on MRI Radiomics to Diagnose Parotid Tumours Before Comparing Performance with Radiologists: A Pilot Study.Journal of imaging informatics in medicine · 2025Article
- MRI Signatures of Parotid Tumours Impacting Management Decisions: A Retrospective Study With Radiology and Pathology Correlation.Journal of medical imaging and radiation oncology · 2025Article
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- Preoperative Direct Puncture Embolization of Castleman Disease of the Parotid Gland: A Case Report.Current oncology (Toronto, Ont.) · 2024Article
- The Rate of Occult Lesion Diagnosis in a Large Bell's Palsy Cohort.The Laryngoscope · 2024Article
- Different MRI-based radiomics models for differentiating misdiagnosed or ambiguous pleomorphic adenoma and Warthin tumor of the parotid gland: a multicenter study.Frontiers in oncology · 2024Article
- Peripheral Nerve Sheath Tumor; an Imposter that Mimics as a Parotid mass.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Rapidly Enlarging Parotid Mass in a Person Living with HIV: A Case of Multiple Myeloma with Extramedullary Plasmacytoma.The American journal of case reports · 2023Article
- The Role of Radiomics in Salivary Gland Imaging: A Systematic Review and Radiomics Quality Assessment.Diagnostics (Basel, Switzerland) · 2022Review
- Unusual presentation of parotid gland adenoid cystic carcinoma : A case presentation and literature review.Radiology case reports · 2022Article
- Multiphasic CT-Based Radiomics Analysis for the Differentiation of Benign and Malignant Parotid Tumors.Frontiers in oncology · 2022Article
- Diagnostic performance of qualitative and radiomics approach to parotid gland tumors: which is the added benefit of texture analysis?The British journal of radiology · 2021Article
- An Overview on the Histogenesis and Morphogenesis of Salivary Gland Neoplasms and Evolving Diagnostic Approaches.Cancers · 2021Review
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- Cross-sectional imaging and cytologic investigations in the preoperative diagnosis of parotid gland tumors - An updated literature review.Bosnian journal of basic medical sciences · 2021Review
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our aim was to define typical magnetic resonance (MRI) findings in malignant and benign parotid tumours. This study is based on retrospective evaluation of pre-surgical MRI of 94 patients with parotid gland tumours. Histology results were available for all tumours. There were 69 cases of benign (73%) and 25 cases of malignant (27%) tumours, including 44 pleomorphic adenomas, 18 Warthin's tumours, 7 various benign tumours, 6 squamous cell carcinomas, 3 carcinoma ex pleomorphic adenomas, 2 mucoepidermoid carcinomas, 1 adenoid cystic carcinoma and 13 various malignant tumours. The following MRI parameters were evaluated: shape, site, size, margins, signal intensity (SI) on T1w and T2w images, contrast enhancement, signal of cystic content, presence or absence of a capsule, perineural spread, extraglandular growth pattern and cervical adenopathy. Statistical analysis was performed to identify the MRI findings most suggestive of malignancy, and to define the most typical MRI pattern of the most common histologies. Ill-defined margins (p < 0.001), adenopathies (p < 0.001) and infiltrative grown pattern (p < 0.001) were significantly predictive of malignancy. Typical findings of pleomorphic adenoma included hyperintensity on T2w images (p = 0.02), strong contrast enhancement (p < 0.001) and lobulated shape (p = 0.04). Typical findings of Warthin's tumour included hyperintense components on T1w images (p < 0.001), location in the parotid inferior process (p < 0.001) and mild or incomplete contrast enhancement (p = 0.01). SI on T1w and T2w images and contrast enhancement enables differential diagnosis between pleomorphic adenoma and Warthin's tumour.
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