Trial reportLymphatic research and biology2016
Effects of Compression Stockings on Elevation of Leg Lymph Pumping Pressure and Improvement of Quality of Life in Healthy Female Volunteers: A Randomized Controlled Trial.
Trial report in Lymphatic research and biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04514939 (Elevate to Alleviate - Evidence Based Nursing Study), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Elevate to Alleviate - Evidence Based Nursing Study
Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Postural differences in the immediate effects of active exercise with compression therapy on lower limb lymphedema.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Trial
- Article
- Treated well but feeling poorly: examining supportive care devices in oncology practice.The oncologist · 2025Article
- The safety and efficacy of compression therapy in patients with stable heart failure.International journal of cardiology. Heart & vasculature · 2024Article
- Article
- The effects of gravity and compression on interstitial fluid transport in the lower limb.Scientific reports · 2022Article
- Compression Stocking Length Effects on Oedema, Pain, and Satisfaction in Nursing Students: A Pilot Randomized Trial.Healthcare (Basel, Switzerland) · 2020Article
- A novel mouse tail lymphedema model for observing lymphatic pump failure during lymphedema development.Scientific reports · 2019Article
- Compression Garments for Medical Therapy and Sports.Polymers · 2018Review
- The relationship between lymphangion chain length and maximum pressure generation established through in vivo imaging and computational modeling.American journal of physiology. Heart and circulatory physiology · 2017Article
- Pump function curve shape for a model lymphatic vessel.Medical engineering & physics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLymph is pumped through the collecting lymphatic vessels by both intrinsic and extrinsic forces. The intrinsic pump relies on spontaneous lymphatic contraction, which generates the pumping lymph pressure (Plp). Among healthy people with daily leg edema, a considerable number of cases are accompanied with low leg Plp. Herein, a double-blinded controlled trial was conducted in healthy female volunteers with reduced leg Plp to compare the effectiveness of a 15-29 mmHg compression stocking (Stocking A) and a 8-16 mmHg stocking (Stocking B) on elevating Plp. METHOD AND
resultsAmong 219 healthy female volunteers who underwent measurement of leg Plp, 80 participants (36.5%) had unilateral or bilateral legs with Plp < 20 mmHg (122 legs with Plp < 20 mmHg and 38 legs with Plp ≧ 20 mmHg). These 80 participants were assigned to wear either Stocking A (n = 40) or Stocking B (n = 40) for 16 weeks. Leg Plp was measured using indocyanine green fluorescence lymphography and an occlusion cuff technique while sitting. At 16 weeks, both Stockings A and B resulted in significantly elevated leg Plp, with the effect on elevating Plp being superior for Stocking A. Only Stocking A resulted in decreased prevalence of leg edema and improved Short Form-36 scores.
conclusionCompression stockings may represent a therapeutic option to elevate leg Plp and ameliorate leg edema, thereby leading to improved quality of life in healthy females with low leg Plp.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.