Evidence map›Paper›PMID 26824725›Full record

ArticleVector borne and zoonotic diseases (Larchmont, N.Y.)2016

Co-Feeding Transmission of the Ehrlichia muris-Like Agent to Mice (Mus musculus).

Sandor E Karpathy, Michelle E J Allerdice, Mili Sheth, Gregory A Dasch, Michael L Levin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vector borne and zoonotic diseases (Larchmont, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Applied and environmental microbiology · 2019
    Article
  7. An Acarological Risk Model Predicting the Density and Distribution of Host-SeekingThe American journal of tropical medicine and hygiene · 2018
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Isolation and Short-Term Persistence of Ehrlichia ewingii in Cell Culture.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandor E Karpathy1 Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services , Atlanta, Georgia .
Michelle E J Allerdice1 Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services , Atlanta, Georgia .
Mili Sheth1 Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services , Atlanta, Georgia .
Gregory A Dasch1 Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services , Atlanta, Georgia .
Michael L Levin1 Rickettsial Zoonoses Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services , Atlanta, Georgia .

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

The Ehrlichia muris-like agent (EMLA) is a newly recognized human pathogen found in Wisconsin and Minnesota. Ecological investigations have implicated both the blacklegged tick, Ixodes scapularis, and the white-footed mouse, Peromyscus leucopus, as playing roles in the maintenance of EMLA in nature. The work presented here shows that I. scapularis is an efficient vector of EMLA in a laboratory mouse model, but that Dermacentor variabilis, another frequent human biting tick found in EMLA endemic areas, is not. Additionally, I. scapularis larvae are able to acquire EMLA through co-feeding with infected nymphs. As EMLA only persists in mouse blood for a relatively short period of time, co-feeding transmission may play an important role in the maintenance of EMLA in ticks, and subsequently may play a role in limiting the geographic distribution of this pathogen in areas where co-feeding of larvae and nymphs is less common.

Indexed as

AnimalsArachnid VectorsDisease Models, AnimalDisease ReservoirsEhrlichiaEhrlichiosisFemaleHumansIxodesLarvaMiceMice, Inbred C57BLMinnesotaNymphPeromyscusRabbitsCo-feedingEhrlichia muris–like agent (EMLA)Ixodes scapularisPeromyscus leucopusTransmission

Identifiers

PMID26824725
PMCPMC4809518

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.