Evidence map›Paper›PMID 26824408›Full record

ArticleInvestigative ophthalmology & visual science2016

The Effect of Limiting the Range of Perimetric Sensitivities on Pointwise Assessment of Visual Field Progression in Glaucoma.

Stuart K Gardiner, William H Swanson, Shaban Demirel

Abstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Validation of the Iowa Head-Mounted Open-Source Perimeter.Translational vision science & technology · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Moving Stimulus Perimetry: A New Functional Test for Glaucoma.Translational vision science & technology · 2022
    Article
  12. Article
  13. Article
  14. Hierarchical Censored Bayesian Analysis of Visual Field Progression.Translational vision science & technology · 2021
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stuart K GardinerDevers Eye Institute Legacy Research Institute, Portland, Oregon, United States.
William H SwansonSchool of Optometry, Indiana University, Bloomington, Indiana, United States.
Shaban DemirelDevers Eye Institute Legacy Research Institute, Portland, Oregon, United States.

Funding

APPLICATION OF PSYCHOPHYSICAL MODELS TO VISUAL DISORDERSR01EY007716 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI SWANSON, WILLIAM H. · 1997 to 2013
$4.7M
3D RNFL Structure And High-Resolution Perimetry For Assessing Glaucomatous DamageR01EY024542 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI SWANSON, WILLIAM H. · 2014 to 2023
$3.2M
Functional Testing for GlaucomaR01EY020922 · NEI · LEGACY EMANUEL HOSPITAL AND HEALTH CENTER · PI GARDINER, STUART · 2011 to 2021
$3.2M
Core Support for Vision Research at Indiana UniversityP30EY019008 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI BURNS, STEPHEN A · 2009 to 2013
$2.1M
Predicting the rate of progression in glaucomaR01EY019674 · NEI · LEGACY EMANUEL HOSPITAL AND HEALTH CENTER · PI DEMIREL, SHABAN · 2009 to 2013
$1.8M
NEI NIH HHS R01 EY007716NEI NIH HHS R01 EY019674NEI NIH HHS R01-EY019674NEI NIH HHS R01 EY020922NEI NIH HHS R01-EY020922NEI NIH HHS R01 EY024542NEI NIH HHS R01-EY024542
6 · The paper itself

Abstract

purposeAutomated perimetry does not produce reliable estimates of true psychophysical threshold in glaucomatous visual fields when the perimetric threshold falls below 15 to 19 dB. It may be possible to truncate testing at such locations and not use stimuli with very high contrast. However, this can only be recommended if it does not harm the ability to monitor change. This study examined the effect of applying such a cutoff by censoring sensitivities in two existing longitudinal datasets.

methodsSeries of six visual fields were taken from participants with glaucoma or high-risk ocular hypertension in the Portland Progression Project (P3) and Rotterdam Eye Study (RES). Pointwise linear regression was used to find "progressing" locations, defined as a slope ≤ -1 dB/y with P < 1%. An eye was labeled progressing if ≥3 locations were progressing. This was repeated after setting any sensitivities below the cutoff value C (CdB) to instead equal that value for different integer values of CdB.

resultsIn the P3 cohort tested using Swedish Interactive Testing Algorithm (SITA) Standard, censoring below 15 to 19 dB did not reduce the number of eyes flagged as progressing. For the RES cohort tested using the Full Threshold algorithm, censoring below 10 dB did not reduce the number of eyes flagged as progressing, but a modest reduction was seen for CdB between 10 dB and 15 to 19 dB.

conclusionsThe proportion of eyes flagged as progressing was not decreased by censoring unreliable sensitivities. Restricting the range of contrast used in clinical perimetry may be possible without hampering the ability to monitor glaucomatous visual field progression.

Indexed as

AlgorithmsIntraocular PressureAdultAgedAged, 80 and overDisease ProgressionFemaleFollow-Up StudiesGlaucomaHumansMaleMiddle AgedVisual FieldsVisual Field Tests

Identifiers

PMID26824408
PMCPMC4736987

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.