ArticleJournal of natural products2016
N-Acyl Dehydrotyrosines, Tyrosinase Inhibitors from the Marine Bacterium Thalassotalea sp. PP2-459.
Article in Journal of natural products, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed, 38 citations in OpenAlex.
- Investigations into the biosynthesis of stieleriacines and related N-acyl tyrosines by comparative genomics, knock-out studies and total synthesis of epi-stieleriacine C.Communications chemistry · 2025Article
- Review
- Aromatic compounds and organic acids identified from Ganoderma formosanum exhibit synergistic anti-melanogenic effects.Journal of food and drug analysis · 2024Article
- Article
- Tyrosinase Inhibitors: A Perspective.Molecules (Basel, Switzerland) · 2023Review
- Genome taxonomy of the genus Thalassotalea and proposal of Thalassotalea hakodatensis sp. nov. isolated from sea cucumber larvae.PloS one · 2023Article
- Effects of Microbial Transformation on the Biological Activities of Prenylated Chalcones fromFoods (Basel, Switzerland) · 2022Article
- Discovery of Novel Tyrosinase Inhibitors From Marine Cyanobacteria.Frontiers in microbiology · 2022Article
- Application of Marine Microbial Natural Products in Cosmetics.Frontiers in microbiology · 2022Review
- The Biosynthesis and Metabolism of theFrontiers in molecular biosciences · 2021Review
- The planctomycete Stieleria maiorica Mal15Communications biology · 2020Article
- Marine-Derived Compounds with Potential Use as Cosmeceuticals and Nutricosmetics.Molecules (Basel, Switzerland) · 2020Review
- Stieleriacines,Frontiers in microbiology · 2020Article
- A comprehensive review on tyrosinase inhibitors.Journal of enzyme inhibition and medicinal chemistry · 2019Review
- Marine Microbial-Derived Molecules and Their Potential Use in Cosmeceutical and Cosmetic Products.Marine drugs · 2017Review
- New Insights into Pathogenic Vibrios Affecting Bivalves in Hatcheries: Present and Future Prospects.Frontiers in microbiology · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
Abstract
Thalassotalic acids A-C and thalassotalamides A and B are new N-acyl dehydrotyrosine derivatives produced by Thalassotalea sp. PP2-459, a Gram-negative bacterium isolated from a marine bivalve aquaculture facility. The structures were elucidated via a combination of spectroscopic analyses emphasizing two-dimensional NMR and high-resolution mass spectrometric data. Thalassotalic acid A (1) displays in vitro inhibition of the enzyme tyrosinase with an IC50 value (130 μM) that compares favorably to the commercially used control compounds kojic acid (46 μM) and arbutin (100 μM). These are the first natural products reported from a bacterium belonging to the genus Thalassotalea.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.