ReviewJournal of oncology2015
Small Cell Carcinoma of the Gallbladder: Case Report and Comprehensive Analysis of Published Cases.
Review in Journal of oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Gallbladder small cell carcinoma from chronic cholecystitis: A case report and review of literature.World journal of gastrointestinal surgery · 2026Article
- Gallbladder Neuroendocrine Neoplasms in Dogs and Humans.Veterinary sciences · 2024Review
- Neuroendocrine Carcinoma of the Gallbladder.Cureus · 2022Article
- Gallbladder Neuroendocrine Tumors: Is There a Need for a Specific Approach?Gastrointestinal tumors · 2022Article
- Primary Small Cell Neuroendocrine Carcinoma of the Gallbladder with Lymph Node Metastasis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- A Rare Case of Gallbladder Small Cell Carcinoma.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Outcomes of metastatic neuroendocrine carcinoma of the gallbladder.Ecancermedicalscience · 2021Article
- Clinicopathological features and survival for gallbladder NEN: a population-based study.Endocrine connections · 2019Article
- Neuroendocrine Carcinoma and Intracystic Papillary Neoplasm: A Rare Association in the Gallbladder.GE Portuguese journal of gastroenterology · 2019Article
- An unusual presentation of carcinoma in gallbladder.CytoJournal · 2019Article
- Incidental small cell carcinoma of the gallbladder-an unexpected finding at elective cholecystectomy.Journal of surgical case reports · 2018Article
- A dural metastatic small cell carcinoma of the gallbladder as the first manifestation: a case report.World journal of surgical oncology · 2018Article
- A Long Survival Woman with Primary Small-Cell Carcinoma of the Gallbladder: Role of Chemotherapy Maintenance.Cureus · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Gallbladder small cell carcinoma is a rare and highly aggressive malignancy with no established standard of care treatment. We described here a case report of small cell gallbladder cancer and we then performed a comprehensive review of 72 case reports of this disease. Methods. Published case reports of small cell carcinoma of the gallbladder between 1983 and 2014 were reviewed. Treatment modalities and survival were analyzed for metastatic and localized disease. Results. Median overall survival for all patients was 13 months. Metastatic disease was identified in 72% of cases. Treatment of metastatic disease with chemotherapy showed a significant survival benefit (p < 0.001) compared to no chemotherapy, and the use of platinum doublet with etoposide showed a nonsignificant 4-month improvement in survival compared to other chemotherapy regimens (p = 0.13). Adjuvant therapy did not demonstrate an improvement of median overall survival in local disease (p = 0.78). Conclusion. Given the limited available data, systemic therapy with platinum and etoposide should be considered for patients with metastatic small cell carcinoma of the gallbladder. Adjuvant chemoradiation or chemotherapy for treatment of local disease warrants further investigation.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.