ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2016
QT interval variability in body surface ECG: measurement, physiological basis, and clinical value: position statement and consensus guidance endorsed by the European Heart Rhythm Association jointly with the ESC Working Group on Cardiac Cellular Electrophysiology.
Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04621032 (Obstructive Sleep Apnea Destabilizes Myocardial Repolarization Homogeneity), which is not on this map. Cited by 108 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Obstructive Sleep Apnea Destabilizes Myocardial Repolarization Homogeneity
Who cites it
108 citing papers in PubMed, 235 citations in OpenAlex.
- Trial
- HIV Infection Is Associated With Variability in Ventricular Repolarization: The Multicenter AIDS Cohort Study (MACS).Circulation · 2020Trial
- Confirmation of the Cardiac Safety of PGFClinical pharmacology in drug development · 2018Trial
- Transcranial direct current stimulation improves the QT variability index and autonomic cardiac control in healthy subjects older than 60 years.Clinical interventions in aging · 2016Trial
- Obesity and shorter QT intervals: sex- and adiposity distribution-specific patterns of ventricular repolarization in healthy Asian youth.BMC cardiovascular disorders · 2026Observational
- From Empirical to More Precise Correction: Multidimensional Performance Evaluation of QTc Formulas in a Cohort of Healthy Asian Youth.Journal of the American Heart Association · 2026Article
- QTc measurement using Apple Watch electrocardiogram in congenital long QT syndrome.European heart journal. Digital health · 2026Article
- Beat-to-Beat QT Variability: A Population Study of the QT Variability Index Composition.Diagnostics (Basel, Switzerland) · 2026Article
- Mechano-electrical feedback in transgenic rabbit models of long QT syndrome Type 2 and short QT syndrome Type 1.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- The effect of oral ciprofloxacin at conventional doses on the QT interval in a tertiary outpatient setting.The Journal of antimicrobial chemotherapy · 2026Article
- AAV9-mediated KCNH2 suppression-replacement gene therapy in a transgenic rabbit model of type 1 short QT syndrome.European heart journal · 2026Article
- Habitual sleep duration and QT variability index: Correlates of ventricular repolarization lability and all-cause mortality.Heart rhythm · 2026Article
- Central adiposity and sex are associated with the integrative architecture of physiological networks in healthy youth: a cross-sectional study in a cohort of Chinese college students.Frontiers in physiology · 2026Article
- Development and validation of a machine learning-based predictive model for new-onset atrial fibrillation after CABG.Frontiers in cardiovascular medicine · 2026Article
- Heart rate variability during wakefulness reflects sleep apnea indicators but remains context-dependent.Frontiers in physiology · 2026Article
- Intra-subject covariates of QT variability indices: influence of ECG noise.Frontiers in physiology · 2026Article
- Case Report: Two cases of recurrent syncope caused byFrontiers in cardiovascular medicine · 2026Article
- Cardiac, respiratory, and gastric rhythms independently modulate motor corticospinal excitability in humans.PLoS biology · 2025Article
- Role of dynamical instability in QT interval variability and early afterdepolarization propensity.Biophysical journal · 2025Article
- Dynamical instability is a major cause of cardiac action potential variability.Biophysical journal · 2025Article
48 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 10 institutions in 6 countries.
Funding
Abstract
This consensus guideline discusses the electrocardiographic phenomenon of beat-to-beat QT interval variability (QTV) on surface electrocardiograms. The text covers measurement principles, physiological basis, and clinical value of QTV. Technical considerations include QT interval measurement and the relation between QTV and heart rate variability. Research frontiers of QTV include understanding of QTV physiology, systematic evaluation of the link between QTV and direct measures of neural activity, modelling of the QTV dependence on the variability of other physiological variables, distinction between QTV and general T wave shape variability, and assessing of the QTV utility for guiding therapy. Increased QTV appears to be a risk marker of arrhythmic and cardiovascular death. It remains to be established whether it can guide therapy alone or in combination with other risk factors. QT interval variability has a possible role in non-invasive assessment of tonic sympathetic activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.