ArticleBMC infectious diseases2016
Multifocal musculoskeletal tuberculosis mimicking multiple bone metastases: a case report.
Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- Article
- Epidemiological and osteoarticular involvement sites' characteristics of multiple osteoarticular tuberculosis: a scoping review.Epidemiology and infection · 2025Article
- Article
- Unveiling diagnostic challenges: A case report of noncontagious vertebral involvement in spinal tuberculosis mimicking metastasis.Radiology case reports · 2024Article
- Disseminated Tuberculosis of the Axial Skeleton.The American journal of tropical medicine and hygiene · 2024Article
- Diagnosis and Treatment of Skipped Multifocal Spinal Tuberculosis Lesions.Orthopaedic surgery · 2023Review
- Multifocal Tuberculous Spondylitis and Extensive Extraspinal Tubercular Osteomyelitis without Immunocompromise: Case Report and Literature Review.Asian journal of neurosurgery · 2023Article
- Multifocal osteolytic tubercular bony lesions masquerading bone metastasis.BMJ case reports · 2022Article
- Necrotizing granulomatous inflammation mimicking skeletal metastasis: a possible differential diagnosis.European journal of hybrid imaging · 2022Article
- Surgical Treatment for Advanced Thoracic Spinal Tuberculosis in Infants: Case Series and Literature Review.International journal of spine surgery · 2022Article
- Multifocal tuberculous osteomyelitis mimicking widespread bony metastases: review of literature and case report.Spinal cord series and cases · 2022Review
- Multifocal bone tuberculosis simulating metastasis.Clinical case reports · 2021Article
- Diffuse lesions secondary to sarcoidosis mimicking widespread metastatic breast cancer: A case report.Clinical case reports · 2021Article
- A Scoring System for Outpatient Orthopedist to Preliminarily Distinguish Spinal Metastasis from Spinal Tuberculosis: A Retrospective Analysis of 141 Patients.Disease markers · 2021Article
- Contiguous Multilevel Vertebral Metastasis in Carcinoma Breast Mimicking Spondylodiscitis.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe occurrence of non-contiguous, multiple, and remote involvement tuberculous spondylitis is rare. The clinical presentation in patients with multifocal musculoskeletal tuberculosis may closely mimic that in patients with multiple bone metastases, which makes the accurate clinical diagnosis challenging. Herein, we report a multifocal musculoskeletal tuberculosis case that was misdiagnosed for 8 months as multiple bone metastases. CASE PRESENTATION: A 63-year-old male farmer of Chinese Han ethnicity presented to us with pain in left side of the neck, right side of the chest and the back for 10 months without typical tuberculosis symptoms. His past medical history, the CT and fluoroscopy-guided biopsy were negative for tuberculosis. Interferon gamma by T-SPOT was also negative. Radiological findings including CT, MRI and PET-CT suggested that the patient had multiple metastases. Accordingly, the patient was misdiagnosed as having musculoskeletal tumors until a swelling under the right nipple ulcerated. The smear test for acid-fast bacilli and the PCR test for TB-DNA of the pus from the swollen area were both positive, leading to the final correct diagnosis of musculoskeletal tuberculosis.
conclusionThe proper diagnosis of musculoskeletal tuberculosis is clinically challenging due to Mycobacterium tuberculosis variants involved and atypical presentations, especially when the lesions are multiple. Our findings indicate that multiple tuberculous spondylitis must be considered in the differential diagnosis of multiple musculoskeletal lesions.
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