Evidence map›Paper›PMID 26823054›Full record

ArticleSurgical endoscopy2016

True NOTES TME resection with splenic flexure release, high ligation of IMA, and side-to-end hand-sewn coloanal anastomosis.

John H Marks, Nicolas Lopez-Acevedo, Barath Krishnan, Matthew N Johnson, Grace A Montenegro, Gerald J Marks

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Robotic Transanal Surgery for Rectal Cancer.Clinics in colon and rectal surgery · 2021
    Review
  4. Article
  5. Article
  6. Article
  7. Transanal Surgery: A History of taTME Ancestry.Clinics in colon and rectal surgery · 2020
    Review
  8. Transanal TME: new standard or fad?Journal of the anus, rectum and colon · 2019
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

John H MarksMarks Colorectal Surgical Associates, Lankenau Institute for Medical Research, Wynnewood, PA, USA. marksj@mlhs.org.
Nicolas Lopez-AcevedoMarks Colorectal Surgical Associates, Lankenau Institute for Medical Research, Wynnewood, PA, USA.
Barath KrishnanMarks Colorectal Surgical Associates, Lankenau Institute for Medical Research, Wynnewood, PA, USA.
Matthew N JohnsonMarks Colorectal Surgical Associates, Lankenau Institute for Medical Research, Wynnewood, PA, USA.
Grace A MontenegroMarks Colorectal Surgical Associates, Lankenau Institute for Medical Research, Wynnewood, PA, USA.
Gerald J MarksMarks Colorectal Surgical Associates, Lankenau Institute for Medical Research, Wynnewood, PA, USA.
Lankenau Institute for Medical Research · USColorectal Surgical Associates · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNatural orifice transluminal endoscopic surgery (NOTES) represents the ultimate expression of minimally invasive surgery. We have developed and present here an initial feasibility and safety study of transanal total mesorectal excision (TME) with splenic flexure release, high ligation of the IMA and IMV, and side-to-end coloanal anastomosis with temporary diverting ileostomy for rectal cancer.

methodsA program of full NOTES TME resection with release of the splenic flexure, high ligation of the IMA/IMV, with side-to-end coloanal anastomosis was performed transanally from December 2013 to July 2014. Demographics, preoperative, perioperative, and postoperative data were prospectively obtained. Operative components were broken into TME, colonic mobilization, splenic flexure release, IMA/IMV transection, transanal extraction of specimen, and coloanal anastomosis for analysis of performance completion.

resultsThere were 3 women and 1 man on whom we operated. Mean age was 56 (46-65). Mean BMI was 26 (23.8-30.2). The operation was completed entirely transanally in 2 patients. Transanal component completion of the operation was as follows: TME in 3/4; colonic mobilization in 4/4; splenic flexure release in 3/4; IMA/IMV transection in 3/4; transanal specimen extraction in 4/4; coloanal anastomosis in 4/4. Abdominal time for completion of component parts was: splenic flexure release 4:53 (min:s), IMA/IMV 19:43, completion of TME 13:41. Mean EBL was 194 cc (25-500). Aside from stoma site, there were no abdominal incisions. There were no mortalities. Mesorectum was intact in all 4 patients and with negative circumferential and distal margins.

conclusionThis experience supports the feasibility and safety of a true NOTES TME. The critical anatomic views demonstrated on video affirm the potential of this approach for distal rectal cancer. Colorectal surgery represents the most logical application for NOTES. While highly promising, a great deal of work remains to develop the technique and applicability of NOTES colorectal surgery.

Indexed as

AgedAnal CanalAnastomosis, SurgicalCarcinomaColonColon, TransverseDigestive System Surgical ProceduresFeasibility StudiesFemaleHumansIleostomyLigationMaleMesenteric Artery, InferiorMesenteryMiddle AgedLaparoscopicNOTESRectal cancerTATATransanal TME

Identifiers

PMID26823054
OpenAlexW2253915857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.