Evidence map›Paper›PMID 26823053›Full record

ArticleSurgical endoscopy2016

Gastric bypass significantly improves quality of life in morbidly obese patients with type 2 diabetes.

Philip Omotosho, Alessandro Mor, Prapimporn Chattranukulchai Shantavasinkul, Leonor Corsino, Alfonso Torquati

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Philip OmotoshoSection of Metabolic and Bariatric Surgery, Rush University Medical Center, Rush University, Chicago, IL, USA.
Alessandro MorDepartment of Surgery, Duke University, Durham, NC, USA.
Prapimporn Chattranukulchai ShantavasinkulDivision of Nutrition and Biochemical Medicine, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Leonor CorsinoDivision of Endocrinology, Metabolism, and Nutrition, Duke University, Durham, NC, USA.
Alfonso TorquatiSection of Metabolic and Bariatric Surgery, Rush University Medical Center, Rush University, Chicago, IL, USA. alfonso_torquati@rush.edu.
Duke University · USRush University Medical Center · USRamathibodi Hospital · TH

Funding

Impact of gastric bypass surgery on risk of CVD in type 2 diabetes mellitusK23DK075907 · NIDDK · VANDERBILT UNIVERSITY · PI TORQUATI, ALFONSO · 2006 to 2009
$594k
NIDDK NIH HHS K23 DK075907
6 · The paper itself

Abstract

objectiveTo evaluate the impact of Roux-en-Y gastric bypass (RYGB) on quality of life in obese diabetic patients compared to standard medical therapy for type 2 diabetes mellitus.

methodsWe prospectively studied two matched obese populations with type 2 diabetes. Thirty patients underwent laparoscopic RYGB and 31 received standard medical therapy combined with a diabetes support and education program (DSE), consisting of educational sessions on diet and exercise. Groups were matched by age, gender, weight, glucostatic parameters, and use of glucose-lowering medications (oral agents and insulin therapy). Health-related quality of life (HRQOL) was assessed using the normalized SF-36 questionnaire, and data were collected at baseline and at 12-month follow-up.

resultsDiabetic patients who underwent RYGB experienced a statistically significant increase in their overall HRQOL. However, the role-physical and mental health domains increased but did not reach statistical significance. Diabetic patients in the medical therapy and DSE group did not show any significant increase in HRQOL. The between-group differences for the HRQOL changes from baseline were significant, other than for role-physical and mental health domains. Percentage changes in glucostatic parameters, discontinuation of glucose-lowering medications, and T2DM remission were not found to predict the percentage change in SF-36 scores at 12 months after RYGB.

conclusionsFor the first time, with a prospective matched control study, we demonstrate a significant improvement in HRQOL in obese diabetic patients who underwent RYGB, but not in those who were offered standard medical therapy and DSE.

Indexed as

Gastric BypassQuality of LifeActivities of Daily LivingAdultCase-Control StudiesDiabetes Mellitus, Type 2ExerciseFemaleHumansHypoglycemic AgentsInsulinLaparoscopyMaleMental HealthMiddle AgedObesity, MorbidHypoglycemic AgentsInsulinBariatric surgeryDiabetesGastric bypassQuality of life

Identifiers

PMID26823053
PMCPMC4912933
OpenAlexW2297510155

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.