ArticleBMC oral health2016
Managing patients taking novel oral anticoagulants (NOAs) in dentistry: a discussion paper on clinical implications.
Article in BMC oral health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- The Effect of Direct Oral Anticoagulant Therapy (DOACs) on oral surgical procedures: a systematic review.BMC oral health · 2023Pooled it
- Local Hemostasis as the Critical Enabler for Safe Antithrombotic Therapy in Dentistry-Navigating Future Frontiers and Innovative Concepts.Journal of clinical medicine · 2026Review
- Review
- Is L-PRF an effective hemostatic agent in single tooth extractions? A cohort study on VKA and DOAC patients.Clinical oral investigations · 2023Observational
- Article
- Perioperative Management of Oral Antithrombotics in Dentistry and Oral Surgery: Part 2.Anesthesia progress · 2023Review
- Experts' consensus on perioperative management of tooth extractions in patients receiving oral antithrombotic treatment.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2022Article
- Consideration of NOACs (novel or non-vitamin K-dependent oral anticoagulants) in dental procedure.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2021Article
- Usefulness of platelet-rich fibrin as a hemostatic agent after dental extractions in patients receiving anticoagulant therapy with factor Xa inhibitors: a case series.Oral and maxillofacial surgery · 2019Article
- Should we fear direct oral anticoagulants more than vitamin K antagonists in simple single tooth extraction? A prospective comparative study.Clinical oral investigations · 2019Article
- Bleeding related to dental treatment in patients taking novel oral anticoagulants (NOACs): a retrospective study.Clinical oral investigations · 2019Article
- Evaluation of the Bleeding Intensity of Patients Anticoagulated with Warfarin or Dabigatran Undergoing Dental Procedures.Arquivos brasileiros de cardiologia · 2018Observational
- Management of dental patients receiving antiplatelet therapy or chronic oral anticoagulation: A review of the latest evidence.The European journal of general practice · 2017Review
- New horizons in anticoagulation: Direct oral anticoagulants and their implications in oral surgery.Medicina oral, patologia oral y cirugia bucal · 2017Review
- Risks of postextraction bleeding after receiving direct oral anticoagulants or warfarin: a retrospective cohort study.BMJ open · 2017Article
- Delayed bleeding after implant surgery in patients taking novel oral anticoagulants: a case report.Journal of dental anesthesia and pain medicine · 2017Article
- Managing patients taking edoxaban in dentistry.Journal of clinical and experimental dentistry · 2017Review
- Dentists' Knowledge, Attitude and Practice in Treating Patients Taking Oral Antithrombotic Medications - A Survey.Journal of clinical and diagnostic research : JCDR · 2017Article
- Perioperative Management in Patients With Undergoing Direct Oral Anticoagulant Therapy in Oral Surgery - A Multicentric Questionnaire Survey.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this paper is to contribute to the discussion on how to approach patients taking new orally administered anticoagulants (NOAs) dabigatran etexilate (a direct thrombin inhibitor), rivaroxaban and apixaban (factor Xa inhibitors), before, during and after dental treatment in light of the more recent knowledges. DISCUSSION: In dentistry and oral surgery, the major concerns in treatment of patients taking direct thrombin inhibitors and factor Xa inhibitors is the risk of haemorrhage and the absence of a specific reversal agent. The degree of renal function, the complexity of the surgical procedure and the patient's risk of bleeding due to other concomitant causes, are the most important factors to consider during surgical dental treatment of patients taking NOAs. For patients requiring simple dental extraction or minor oral surgery procedures, interruption of NOA is not generally necessary, while an higher control of bleeding and discontinuation of the drug (at least 24 h) should be requested before invasive surgical procedures, depending on renal functionality. The clinician has to consider that the number of patients taking NOAs is rapidly increasing. Since available data are not sufficient to establish an evidence-based dental management, the dentist must use caution and attention when treating patients taking dabigatran, rivaroxaban and apixaban.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.