ReviewProgress in brain research2016
Genetic imaging consortium for addiction medicine: From neuroimaging to genes.
Abstract readReview
In one paragraph
Review in Progress in brain research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity: A Systematic Review.JAMA psychiatry · 2024Pooled it
- ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries.Translational psychiatry · 2020Pooled it
- Identifying impulsivity and substance use measures in neuroimaging datasets: A scoping review and searchable dataset repository for researchers.Current addiction reports · 2026Article
- Artificial intelligence approaches for anti-addiction drug discovery.Digital discovery · 2025Review
- Reporting checklists in neuroimaging: promoting transparency, replicability, and reproducibility.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Neuroimaging Biomarkers in Addiction.medRxiv : the preprint server for health sciences · 2024Article
- Recalibrating single-study effect sizes using hierarchical Bayesian models.Frontiers in neuroimaging · 2023Article
- The Genetically Informed Neurobiology of Addiction (GINA) model.Nature reviews. Neuroscience · 2023Review
- The evolution of Big Data in neuroscience and neurology.Journal of big data · 2023Article
- Identifying alcohol misuse biotypes from neural connectivity markers and concurrent genetic associations.Translational psychiatry · 2022Article
- Shared Genetic Etiology between Cortical Brain Morphology and Tobacco, Alcohol, and Cannabis Use.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Subcortical surface morphometry in substance dependence: An ENIGMA addiction working group study.Addiction biology · 2020Article
- Sex Differences in the Effect of Nucleus Accumbens Volume on Adolescent Drinking: The Mediating Role of Sensation Seeking in the NCANDA Sample.Journal of studies on alcohol and drugs · 2019Article
- Mega-Analysis of Gray Matter Volume in Substance Dependence: General and Substance-Specific Regional Effects.The American journal of psychiatry · 2019Article
- A Roadmap for Integrating Neuroscience Into Addiction Treatment: A Consensus of the Neuroscience Interest Group of the International Society of Addiction Medicine.Frontiers in psychiatry · 2019Review
- Glioma Migration Through the Corpus Callosum and the Brainstem Detected by Diffusion and Magnetic Resonance Imaging: Initial Findings.Frontiers in human neuroscience · 2019Article
- The Influence of DAT1, COMT, and BDNF Genetic Polymorphisms on Total and Subregional Hippocampal Volumes in Early Onset Heavy Cannabis Users.Cannabis and cannabinoid research · 2018Article
- ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide.NeuroImage · 2017Review
- The Neurobiology of Cannabis Use Disorders: A Call for Evidence.Frontiers in behavioral neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
47 authors.
Scott MackeyDepartments of Psychiatry and Psychology, University of Vermont, Burlington, VT, USA. Electronic address: msmackey@uvm.edu.
Kees-Jan KanDepartments of Psychiatry and Psychology, University of Vermont, Burlington, VT, USA.
Bader ChaaraniDepartments of Psychiatry and Psychology, University of Vermont, Burlington, VT, USA.
Nelly Alia-KleinDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Albert BatallaDepartment of Psychiatry and Psychology, Hospital Clínic, IDIBAPS, CIBERSAM, University of Barcelona, Barcelona, Spain; Department of Psychiatry, Radboud University Medical Centre, Nijmegen, The Netherlands.
Samantha BrooksDepartment of Psychiatry and MRC Unit on Anxiety & Stress Disorders, University of Cape Town, Cape Town, South Africa.
Janna CousijnDepartment of Psychiatry and MRC Unit on Anxiety & Stress Disorders, University of Cape Town, Cape Town, South Africa.
Alain DagherMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
Michiel de RuiterDepartment of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Sylvane DesrivieresInstitute of Psychiatry, King's College London, London, UK.
Sarah W Feldstein EwingDepartment of Psychiatry, Oregon Health & Science University, Portland, OR, USA.
Rita Z GoldsteinDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Anna E GoudriaanDepartment of Psychiatry and MRC Unit on Anxiety & Stress Disorders, University of Cape Town, Cape Town, South Africa; Department of Psychiatry, University of Amsterdam, Amsterdam, The Netherlands.
Mary M HeitzegDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Kent HutchisonDepartment of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO, USA.
Chiang-Shan R LiDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Edythe D LondonDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA; David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Valentina LorenzettiSchool of Psychological Sciences, Monash Institute of Cognitive and Clinical Neurosciences and Monash Biomedical Imaging, Monash University, Melbourne, Australia.
Maartje LuijtenBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands.
Rocio Martin-SantosDepartment of Psychiatry and Psychology, Hospital Clínic, IDIBAPS, CIBERSAM, University of Barcelona, Barcelona, Spain.
Angelica M MoralesDavid Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.
Martin P PaulusVA San Diego Healthcare System and Department of Psychiatry, University of California San Diego, La Jolla, CA, USA; Laureate Institute for Brain Research, Tulsa, OK, USA.
Tomas PausRotman Research Institute, University of Toronto, Toronto, ON, Canada.
Godfrey PearlsonDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Renée SchluterDepartment of Psychiatry, University of Amsterdam, Amsterdam, The Netherlands.
Reza MomenanSection on Brain Electrophysiology and Imaging, Institute on Alcohol Abuse and Alcoholism, Bethesda, USA.
Lianne SchmaalDepartment of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.
Gunter SchumannInstitute of Psychiatry, King's College London, London, UK.
Rajita SinhaDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Zsuzsika SjoerdsMax Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Dan J SteinDepartment of Psychiatry and MRC Unit on Anxiety & Stress Disorders, University of Cape Town, Cape Town, South Africa.
Elliot A SteinIntramural Research Program-Neuroimaging Research Branch, National Institute on Drug Abuse, Baltimore, MD, USA.
Nadia SolowijSchool of Psychology, University of Wollongong, Wollongong, NSW, Australia.
Susan TapertLaureate Institute for Brain Research, Tulsa, OK, USA.
Anne UhlmannDepartment of Psychiatry and MRC Unit on Anxiety & Stress Disorders, University of Cape Town, Cape Town, South Africa.
Dick VeltmanDepartment of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.
Ruth van HolstDepartment of Psychiatry, University of Amsterdam, Amsterdam, The Netherlands.
Henrik WalterDepartment of Psychiatry and Psychotherapy, Charité Universitatsmedizin, Berlin, Germany.
Margaret J WrightQIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Murat YucelSchool of Psychological Sciences, Monash Institute of Cognitive and Clinical Neurosciences and Monash Biomedical Imaging, Monash University, Melbourne, Australia.
Deborah Yurgelun-ToddDepartment of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT, USA.
Derrek P HibarDepartment of Neurology, Imaging Genetics Center, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.
Neda JahanshadDepartment of Neurology, Imaging Genetics Center, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.
Paul M ThompsonDepartment of Neurology, Imaging Genetics Center, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.
David C GlahnDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Hugh GaravanDepartments of Psychiatry and Psychology, University of Vermont, Burlington, VT, USA.
Patricia ConrodDepartment of Psychiatry, Université de Montreal, CHU Ste Justine Hospital, Montreal, QC, Canada.
Funding
Vermont Center on Behavior and HealthP20GM103644 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SIGMON, STACEY C · 2013 to 2022
$21.3MBrain Imaging of Human Drug AbuseZIADA000470 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI STEIN, ELLIOT A · 2009 to 2021
$15.8MSex Differences in Stress Related RelapseP50DA016556 · NIDA · YALE UNIVERSITY · PI SINHA, RAJITA · 2002 to 2011
$10.4MTraining U54EB020403 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2014 to 2018
$10.1MENIGMA- Addiction: Pooling of Existing Datasets to Identify Brain and Genetic Correlates of Addiction, Next StepsR01DA047119 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HUGH P. GARAVAN · 2018 to 2026
$5.4MInterdisciplinary Research on Stress, Self-Control & AddictionUL1DE019586 · NIDCR · YALE UNIVERSITY · PI SINHA, RAJITA · 2008 to 2011
$5.0MProtocols, Statistics, Collaborative Method Development and ToolsPL1DA024859 · NIDA · YALE UNIVERSITY · PI SINHA, RAJITA · 2007 to 2011
$3.6MEffect of Prazosin on Alcohol Craving, Stress Dysregulation and Alcohol RelapseR01AA020504 · NIAAA · YALE UNIVERSITY · PI FOX, HELEN CECILIA, SINHA, RAJITA · 2012 to 2016
$2.7MCerebral Correlates of Early Habitual DrinkingR01AA021449 · NIAAA · YALE UNIVERSITY · PI LI, CHIANG-SHAN RAY · 2013 to 2017
$1.2MInterdisciplinary Research on Stress, Self-Control & AddictionUL1RR024925 · NCRR · YALE UNIVERSITY · PI SINHA, RAJITA · 2007 to 2007
$849kENIGMA-Addiction: A Data-Pooling of Brain and Genetic Correlates of AddictionR21DA038381 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI GARAVAN, HUGH P. · 2014 to 2015
$442kNCRR NIH HHS UL1 RR024925NIAAA NIH HHS R01 AA020504NIAAA NIH HHS R01 AA021449NIBIB NIH HHS U54 EB 020403NIBIB NIH HHS U54 EB020403NIDA NIH HHS 1R21DA038381NIDA NIH HHS P50 DA016556NIDA NIH HHS PL1 DA024859NIDA NIH HHS R01 DA047119NIDA NIH HHS R21 DA038381NIDCR NIH HHS UL1 DE019586NIGMS NIH HHS 1P20GM103644-01A1NIGMS NIH HHS P20 GM103644
Abstract
Since the sample size of a typical neuroimaging study lacks sufficient statistical power to explore unknown genomic associations with brain phenotypes, several international genetic imaging consortia have been organized in recent years to pool data across sites. The challenges and achievements of these consortia are considered here with the goal of leveraging these resources to study addiction. The authors of this review have joined together to form an Addiction working group within the framework of the ENIGMA project, a meta-analytic approach to multisite genetic imaging data. Collectively, the Addiction working group possesses neuroimaging and genomic data obtained from over 10,000 subjects. The deadline for contributing data to the first round of analyses occurred at the beginning of May 2015. The studies performed on this data should significantly impact our understanding of the genetic and neurobiological basis of addiction.
Indexed as
NeuroimagingBrainGenetic TestingHumansMeta-Analysis as TopicPhenotypeSubstance-Related DisordersAddictionENIGMAGenetic imagingNeuroimaging
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