ArticleMalaria journal2016
Concurrent malaria and arbovirus infections in Kedougou, southeastern Senegal.
Article in Malaria journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 11 of them syntheses that pooled it.
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Who cites it
76 citing papers in PubMed, 11 syntheses or guidelines pooled it, 128 citations in OpenAlex.
- Viral and host determinants of arboviral disease severity in African populations: A systematic review with meta-analysis.PLoS neglected tropical diseases · 2026Pooled it
- Tick-Borne Diseases in Sub-Saharan Africa: A Systematic Review of Pathogens, Research Focus, and Implications for Public Health.Pathogens (Basel, Switzerland) · 2024Pooled it
- Worldwide distribution, symptoms and diagnosis of the coinfections between malaria and arboviral diseases: a systematic review.Memorias do Instituto Oswaldo Cruz · 2024Pooled it
- Increasing prevalence of malaria and acute dengue virus coinfection in Africa: a meta-analysis and meta-regression of cross-sectional studies.Malaria journal · 2023Pooled it
- Analysis of dengue fever disease in West Africa.Experimental biology and medicine (Maywood, N.J.) · 2023Pooled it
- Contemporary epidemiological data of Rift Valley fever virus in humans, mosquitoes and other animal species in Africa: A systematic review and meta-analysis.Veterinary medicine and science · 2023Pooled it
- Epidemiology of yellow fever virus in humans, arthropods, and non-human primates in sub-Saharan Africa: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2022Pooled it
- Chikungunya fever in Africa: a systematic review.Pathogens and global health · 2020Pooled it
- Prevalence and laboratory analysis of malaria and dengue co-infection: a systematic review and meta-analysis.BMC public health · 2019Pooled it
- Global prevalence and distribution of coinfection of malaria, dengue and chikungunya: a systematic review.BMC public health · 2018Pooled it
- Pooled it
- Study of patients with acute undifferentiated fever identifies dengue as a growing threat to public health in Mali.PLoS neglected tropical diseases · 2026Article
- Article
- Whose Line Is it Anyway? Defining Seropositivity Cutoffs for Infectious Disease Surveillance.The Journal of infectious diseases · 2026Article
- Mining corridors as emergence interfaces: an evidence-informed one health operational framework for prevention of infectious disease outbreaks in Kédougou, Senegal.Frontiers in public health · 2026Review
- Arboviruses circulation in Guinea: Overview and perspectives for public health.PLoS neglected tropical diseases · 2026Review
- Coinfection of Malaria and Dengue Fever in Patients With Acute Undifferentiated Febrile Illnesses in Ghana: A Narrative Review.BioMed research international · 2026Review
- Common Molecular Detection of the Neglected Human Malaria Parasite Among Febrile Patients in Southern Regions in Senegal.Pathogens (Basel, Switzerland) · 2025Article
- Challenging the notion of Aedes aegypti as the primary chikungunya virus vector: insights from Kédougou, Southeastern Senegal.BMC infectious diseases · 2025Article
- Inter-epidemic seroprevalence of Rift Valley fever virus and associated risk factors in humans in Eastern Rwanda.PLoS neglected tropical diseases · 2025Article
16 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundMalaria is one of the leading causes of acute febrile illness (AFI) in Africa. With the advent of malaria rapid diagnostic tests, misdiagnosis and co-morbidity with other diseases has been highlighted by an increasing number of studies. Although arboviral infections and malaria are both vector-borne diseases and often have an overlapping geographic distribution in sub-Saharan Africa, information about their incidence rates and concurrent infections is scarce.
methodsFrom July 2009 to March 2013 patients from seven healthcare facilities of the Kedougou region presenting with AFI were enrolled and tested for malaria and arboviral infections, i.e., yellow fever (YFV), West Nile (WNV), dengue (DENV), chikungunya (CHIKV), Crimean Congo haemorrhagic fever (CCHFV), Zika (ZIKV), and Rift Valley fever viruses (RVFV). Malaria parasite infections were investigated using thick blood smear (TBS) and rapid diagnostics tests (RDT) while arbovirus infections were tested by IgM antibody detection (ELISA) and RT-PCR assays. Data analysis of single or concurrent malaria and arbovirus was performed using R software.
resultsA total of 13,845 patients, including 7387 with malaria and 41 with acute arbovirus infections (12 YFV, nine ZIKV, 16 CHIKV, three DENV, and one RVFV) were enrolled. Among the arbovirus-infected patients, 48.7% (20/41) were co-infected with malaria parasites at the following frequencies: CHIKV 18.7% (3/16), YFV 58.3% (7/12), ZIKV 88.9% (8/9), DENV 33.3% (1/3), and RVF 100% (1/1). Fever ≥40 °C was the only sign or symptom significantly associated with dual malaria parasite/arbovirus infection.
conclusionsConcurrent malaria parasite and arbovirus infections were detected in the Kedougou region from 2009 to 2013 and need to be further documented, including among asymptomatic individuals, to assess its epidemiological and clinical impact.
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