Evidence map›Paper›PMID 26821531›Full record

ArticleBMC bioinformatics2016

Methods for the integration of multi-omics data: mathematical aspects.

Matteo Bersanelli, Ettore Mosca, Daniel Remondini, Enrico Giampieri, Claudia Sala, Gastone Castellani, Luciano Milanesi

Abstract read
In one paragraph

Article in BMC bioinformatics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 214 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
214citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

214 citing papers in PubMed, 1 synthesis or guideline pooled it.

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154 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matteo BersanelliDepartment of Physics and Astronomy, Universita' di Bologna, Via B. Pichat 6/2, Bologna, 40127, Italy. matteo.bersanelli@studio.unibo.it.
Ettore MoscaInstitute of Biomedical Technologies - CNR, Via Fratelli Cervi 93, Segrate MI, 20090, Italy. ettore.mosca@itb.cnr.it.
Daniel RemondiniDepartment of Physics and Astronomy, Universita' di Bologna, Via B. Pichat 6/2, Bologna, 40127, Italy. daniel.remondini@unibo.it.
Enrico GiampieriDepartment of Physics and Astronomy, Universita' di Bologna, Via B. Pichat 6/2, Bologna, 40127, Italy. enrico.giampieri@unibo.it.
Claudia SalaDepartment of Physics and Astronomy, Universita' di Bologna, Via B. Pichat 6/2, Bologna, 40127, Italy. claudia.sala@studio.unibo.it.
Gastone CastellaniDepartment of Physics and Astronomy, Universita' di Bologna, Via B. Pichat 6/2, Bologna, 40127, Italy. gastone.castellani@unibo.it.
Luciano MilanesiInstitute of Biomedical Technologies - CNR, Via Fratelli Cervi 93, Segrate MI, 20090, Italy. luciano.milanesi@itb.cnr.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMethods for the integrative analysis of multi-omics data are required to draw a more complete and accurate picture of the dynamics of molecular systems. The complexity of biological systems, the technological limits, the large number of biological variables and the relatively low number of biological samples make the analysis of multi-omics datasets a non-trivial problem. RESULTS AND

conclusionsWe review the most advanced strategies for integrating multi-omics datasets, focusing on mathematical and methodological aspects.

Indexed as

Models, GeneticAlgorithmsBayes TheoremGenomicsHumansLeast-Squares AnalysisSoftware

Identifiers

PMID26821531
PMCPMC4959355

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.