ArticlePloS one2016
Relevant Obstetric Factors for Cerebral Palsy: From the Nationwide Obstetric Compensation System in Japan.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between maternal overweight or obesity and cerebral palsy in children: A meta-analysis.PloS one · 2018Pooled it
- Maternal, Labor, Delivery, and Perinatal Outcomes Associated with Placental Abruption: A Systematic Review.American journal of perinatology · 2017Pooled it
- Causes and risk factors for singleton stillbirth in Japan: Analysis of a nationwide perinatal database, 2013-2014.Scientific reports · 2018Trial
- A Randomized, Placebo-Controlled Trial of Human Umbilical Cord Blood Mesenchymal Stem Cell Infusion for Children With Cerebral Palsy.Cell transplantation · 2018Trial
- Characteristics of Pregnancy Course in an Infant With Cerebral Palsy Showing Decreased Fetal Movement.Obstetrics and gynecology international · 2026Article
- Fetal heart rate evolution patterns associated with umbilical cord abnormalities in term fetuses: a single center population-based study.BMC pregnancy and childbirth · 2025Article
- Prevention of fetal brain injury in category II tracings.Acta obstetricia et gynecologica Scandinavica · 2023Article
- Association of placental and umbilical cord characteristics with cerebral palsy: national cohort study.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2023Article
- Determinants of cerebral palsy in children: systematic review.Sudanese journal of paediatrics · 2023Review
- The Association of Placental Abruption and Pediatric Neurological Outcome: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
- Correlation between fetal heart rate evolution patterns and magnetic resonance imaging findings in severe cerebral palsy: A longitudinal study.BJOG : an international journal of obstetrics and gynaecology · 2022Article
- Fetal heart rate evolution patterns in cerebral palsy associated with umbilical cord complications: a nationwide study.BMC pregnancy and childbirth · 2022Article
- Stem Cell Therapies for Cerebral Palsy and Autism Spectrum Disorder-A Systematic Review.Brain sciences · 2021Review
- Placental abruption in each hypertensive disorders of pregnancy phenotype: a retrospective cohort study using a national inpatient database in Japan.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Risk factors for cerebral palsy in neonates due to placental abruption.The journal of obstetrics and gynaecology research · 2021Article
- Weekend and off-hour effects on the incidence of cerebral palsy: contribution of consolidated perinatal care.Environmental health and preventive medicine · 2020Article
- Current Status of the Obstetric Compensation System for Cases of Cerebral Palsy at a General Hospital in Tochigi, Japan.Global pediatric health · 2020Article
- Management of disseminated intravascular coagulation associated with placental abruption and measures to improve outcomes.Obstetrics & gynecology science · 2019Review
- Development and exploration of a Japanese version of the cerebral palsy quality of life for children questionnaire for primary caregivers: a pilot study.Journal of physical therapy science · 2019Article
- Impact of Long-Term Hippotherapy on the Walking Ability of Children With Cerebral Palsy and Quality of Life of Their Caregivers.Frontiers in neurology · 2019Article
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to identify the relevant obstetric factors for cerebral palsy (CP) after 33 weeks' gestation in Japan. STUDY
designThis retrospective case cohort study (1:100 cases and controls) used a Japanese national CP registry. Obstetric characteristics and clinical course were compared between CP cases in the Japan Obstetric Compensation System for Cerebral Palsy database and controls in the perinatal database of the Japan Society of Obstetrics and Gynecology born as live singleton infants between 2009 and 2011 with a birth weight ≥ 2,000 g and gestation ≥ 33 weeks.
resultsOne hundred and seventy-five CP cases and 17,475 controls were assessed. Major relevant single factors for CP were placental abnormalities (31%), umbilical cord abnormalities (15%), maternal complications (10%), and neonatal complications (1%). A multivariate regression model demonstrated that obstetric variables associated with CP were acute delivery due to non-reassuring fetal status (relative risk [RR]: 37.182, 95% confidence interval [CI]: 20.028-69.032), uterine rupture (RR: 24.770, 95% CI: 6.006-102.160), placental abruption (RR: 20.891, 95% CI: 11.817-36.934), and preterm labor (RR: 3.153, 95% CI: 2.024-4.911), whereas protective factors were head presentation (RR: 0.199, 95% CI: 0.088-0.450) and elective cesarean section (RR: 0.236, 95% CI: 0.067-0.828).
conclusionCP after 33 weeks' gestation in the recently reported cases in Japan was strongly associated with acute delivery due to non-reassuring fetal status, uterine rupture, and placental abruption.
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