Evidence map›Paper›PMID 26820988›Full record

GuidelineEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2016

ESTES guidelines: acute mesenteric ischaemia.

J V T Tilsed, A Casamassima, H Kurihara, D Mariani, I Martinez, J Pereira, L Ponchietti, A Shamiyeh, F Al-Ayoubi, L A B Barco and 12 more

3 registry-linked trialsOpen access · hybridAbstract readPractice Guideline
In one paragraph

Guideline in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 131 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 5 pooled it
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04361110 completednot on this map

Preoperative Findings on Non-specific CT in Patients With Primary Acute Intestinal Ischaemia; a Case-control Study

TypeobservationalSponsorAalborg University HospitalRan2006 to 2009Enrolled130ConditionsAcute Intestinal IschemiaArmsComputerized tomography scan of the abdomen
NCT04688879 completednot on this mapstarted 2020, after this paper: background citation

Thrombolysis With Intra-arterial Urokinase for Acute Superior Mesenteric Artery Occlusion: Outcome Analysis

TypeobservationalSponsorChang Gung Memorial HospitalRan2020 to 2020Enrolled13ConditionsArterial Occlusion Mesenteric Artery SuperiorArmsintra-arterial urokinase thrombolysis
NCT05665946 completednot on this map

Acute Intestinal Ischaemia: the Preoperative Diagnostic Approach

TypeobservationalSponsorAalborg University HospitalRan2015 to 2019Enrolled2,958ConditionsAcute Mesenteric IschemiaArmsBlood sample analysis
3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 5 syntheses or guidelines pooled it, 372 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. The real-world management of acute mesenteric ischemia in Spain: results from a multicenter national survey.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Observational
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Nonocclusive Mesenteric Ischemia: A Review for Interventional Radiologists.Interventional radiology (Higashimatsuyama-shi (Japan) · 2025
    Review

71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 19 institutions in 10 countries.

J V T TilsedSurgery Health Care Group, Hull and East Yorkshire Hospitals NHS Trust, Hull, UK. jonathan.tilsed@hey.nhs.uk.
A CasamassimaEmergency Department, Istituto Clinico Città Studi, Milan, Italy.
H KuriharaEmergency Surgery and Trauma Unit, Humanitas Research Hospital, Rozzano, Italy.
D MarianiDepartment of General Surgery, Ospedale di Legnano, Milan, Italy.
I MartinezServicio de Cirugía General y Digestiva, Hospital Universitario de Torrevieja, Torrevieja, Spain.
J PereiraSurgery 1-Tondela-Viseu Hospital Centre, Viseu, Portugal.
L PonchiettiDepartment of Surgery, Milton Keynes Hospital NHS Foundation Trust, Milton Keynes, UK.
A Shamiyeh2nd Surgical Department, Kepler University Clinic Linz, Linz, Austria.
F Al-AyoubiDivision of Trauma and Acute Care Surgery, Mafraq Hospital, Abu Dhabi, United Arab Emirates.
L A B BarcoDepartment of Angiology and Vacular Surgery, University Hospital of Torrevieja, Torrevieja, Spain.
M CeolinEmergency Surgery and Trauma Unit, Humanitas Research Hospital, Rozzano, Italy.
A J G D'AlmeidaDepartment of General Surgery, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
S Hilario2nd Surgical Department, Santo André Hospital, Leiria, Portugal.
A L OlavarriaServicio de Cirugía General y Digestiva, Hospital Galdakao Usansolo, Vizcaya, Spain.
M M OzmenDepartment of Surgery, Medical School, Hacettepe University, 06100, Ankara, Turkey.
L F PinheiroGeneral Surgery Department, Hospital São Teotónio, Viseu, Portugal.
M PoezeDepartment of Surgery/Intensive Care Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.
G TriantosDepartment of General Surgery, Rhodes General Hospital, Rhodes, Greece.
F T FuentesGeneral Surgery 2 and Emergency Surgery, University General Hospital Gregorio Marañón, Madrid, Spain.
S U SierraDepartment of Surgery, Galdakao-Usansolo Hospital, Galdakao, Vizcaya, Spain.
K SoreideDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
H YanarDepartment of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Çapa, Istanbul, Turkey.
Hospital de Galdakao · ESIRCCS Humanitas Research Hospital · ITAzienda Ospedaliera Ospedale Civile di Legnano · ITCentro Hospitalar de Vila Nova de Gaia · PTCentro Hospitalar Tondela-Viseu · PTGeneral Hospital of Rhodes · GRHacettepe University · TRHospital de Santo António · PTHospital General Universitario Gregorio Marañón · ESHospital Quirón Torrevieja · ESHospital São Teotónio · PTHull and East Yorkshire Hospitals NHS Trust · GBIstanbul University · TRIstituto di Sessuologia Clinica · ITKepler Universitätsklinikum · ATMaastricht University · NLMafraq Hospital · AEMilton Keynes Hospital NHS Foundation Trust · GBUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAcute mesenteric ischaemia (AMI) accounts for about 1:1000 acute hospital admissions. Untreated, AMI will cause mesenteric infarction, intestinal necrosis, an overwhelming inflammatory response and death. Early intervention can halt and reverse this process leading to a full recovery, but the diagnosis of AMI is difficult and failure to recognize AMI before intestinal necrosis has developed is responsible for the high mortality of the disease. Early diagnosis and prompt treatment are the goals of modern therapy, but there are no randomized controlled trials to guide treatment and the published literature contains a high ratio of reviews to original data. Much of that data comes from case reports and often small, retrospective series with no clearly defined treatment criteria.

methodsA study group of the European Society for Trauma and Emergency Surgery (ESTES) was formed in 2013 with the aim of developing guidelines for the management of AMI. A comprehensive literature search was performed using the Medical Subject Heading (MeSH) thesaurus keywords "mesenteric ischaemia", "bowel ischaemia" and "bowel infarction". The bibliographies of relevant articles were screened for additional publications. After an initial systematic review of the literature by the whole group, a steering group formulated questions using a modified Delphi process. The evidence was then reviewed to answer these questions, and recommendations formulated and agreed by the whole group.

resultsThe resultant recommendations are presented in this paper.

conclusionsThe aim of these guidelines is to provide recommendations for practice that will lead to improved outcomes for patients.

Indexed as

Mesenteric IschemiaAnti-Bacterial AgentsAnticoagulantsEarly DiagnosisEarly Medical InterventionFluid TherapyHumansMultidetector Computed TomographyOxygen Inhalation TherapyRisk AssessmentSymptom AssessmentVascular Surgical ProceduresAnti-Bacterial AgentsAnticoagulantsAcute mesenteric ischaemiaClinical managementDiagnosisGuidelines

Identifiers

PMID26820988
PMCPMC4830881
OpenAlexW2292482254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.