Evidence map›Paper›PMID 26820958›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2016

Analysis of Invadopodia Formation in Breast Cancer Cells.

Ziqing Wang, Xiao Liang, Ming Cai, Guangwei Du

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ziqing WangDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, 6431 Fannin St, Houston, TX, 77030, USA.
Xiao LiangDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, 6431 Fannin St, Houston, TX, 77030, USA.
Ming CaiDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, 6431 Fannin St, Houston, TX, 77030, USA.
Guangwei DuDepartment of Integrative Biology and Pharmacology, The University of Texas Health Science Center at Houston, 6431 Fannin St, Houston, TX, 77030, USA. guangwei.du@uth.tmc.edu.

Funding

Phospholipase D2 regulation of vascular smooth muscle cell migrationR01HL119478 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DU, GUANGWEI · 2014 to 2017
$1.5M
NHLBI NIH HHS R01 HL119478NHLBI NIH HHS R01HL119478
6 · The paper itself

Abstract

Metastasis is the major cause of breast cancer deaths. To spread from the primary tumor sites to distant tissues, solid tumor cells need to degrade the surrounding extracellular matrix (ECM). The protrusive membrane structures named invadopodia have been shown to play a critical role in the degradation of the ECM and invasion of invasive cancer cells. In this chapter, we describe a detailed protocol to examine invadopodia in human breast cancer cells.

Indexed as

Breast NeoplasmsCell Line, TumorCytological TechniquesFluorescent DyesGelatinHumansNeoplasm InvasivenessPodosomesFluorescent DyesGelatinBreast cancerExtracellular matrixInvadopodiaInvasionMetastasis

Identifiers

PMID26820958
PMCPMC5152756

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.