Evidence map›Paper›PMID 26820845›Full record

ArticleClinical and experimental nephrology2017

The association of hypercalciuria and hyperuricosuria with vesicoureteral reflux in children.

Abolfazl Mahyar, Reza Dalirani, Parviz Ayazi, Samaneh Hamzehloo, Seyed Alireza Moshiri, Negin Khoshbakht Ahmadi, Sara Talebi Pour Nikoo, Zohreh Yazdi, Shiva Esmaeily

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Article in Clinical and experimental nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Abolfazl MahyarDepartment of Pediatrics, Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran. Abolfazl473@yahoo.com.
Reza DaliraniDepartment of Pediatric Nephrology, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Parviz AyaziDepartment of Pediatrics, Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
Samaneh HamzehlooDepartment of Pediatrics, Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
Seyed Alireza MoshiriDepartment of Pediatrics, Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
Negin Khoshbakht AhmadiDepartment of Pediatrics, Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
Sara Talebi Pour NikooDepartment of Pediatrics, Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
Zohreh YazdiDepartment of Pediatrics, Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.
Shiva EsmaeilyDepartment of Pediatrics, Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOne of the important complications of vesicoureteral reflux (VUR) is the development of urolithiasis. Identifying factors involved in development of urolithiasis in children with VUR is immensely important. This study was conducted to determine the association between hypercalciuria and hyperuricosuria with VUR in children.

methodsOne-hundred children with VUR (case group) were compared to 100 healthy children (control group) in terms of hypercalciuria and hyperuricosuria. To measure these markers, random morning fasting urine samples were used. Data were analyzed using statistical tests.

resultsHypercalciuria and hyperuricosuria frequencies, and also urine calcium/creatinine (Ca/Cr) and urine uric acid/creatinine (UA/Cr) ratios were significantly higher in the case group compared to the control group (P < 0.05). A significant difference was found between hypercalciuria and hyperuricosuria in severity of VUR (P < 0.05). A positive correlation was observed between hypercalciuria and hyperuricosuria and severity of VUR (P < 0.05).

conclusionsThe present study showed that there is association between hypercalciuria, hyperuricosuria and VUR in children. It is recommended to adopt measures to prevent the development of urolithiasis in VUR patients.

Indexed as

BiomarkersCalciumCase-Control StudiesChildChild, PreschoolCreatinineFemaleHumansHypercalciuriaInfantInfant, NewbornMaleRisk FactorsUric AcidUrolithiasisVesico-Ureteral RefluxBiomarkersCalciumCreatinineUric AcidChildrenHypercalciuriaHyperuricosoriaUrolithiasisVesicoureteral reflux

Identifiers

PMID26820845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.