Evidence map›Paper›PMID 26820604›Full record

ArticleSubstance abuse

Internal medicine resident knowledge, attitudes, and barriers to naloxone prescription in hospital and clinic settings.

J Deanna Wilson, Natalie Spicyn, Pamela Matson, Anika Alvanzo, Leonard Feldman

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Substance abuse. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04677387 nacompletednot on this map

Addressing the Opioid Epidemic Through Community Pharmacy Engagement: Randomized Controlled Trial (Aim 2)

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2021 to 2023Enrolled48ConditionsNaloxoneArmsNalox-comm Training Module, Prescribe to Prevent: Overdose Prevention and Naloxone Rescue Kits for Prescribers and Pharmacists
NCT06843213 narecruitingnot on this map

Teaching Health Promotion and Resilience in Varied Environments: a Peer-led Intervention Following Hospital Discharge

TypeinterventionalSponsorUniversity of PennsylvaniaRan2025 to 2028Enrolled390ConditionsOpioid Use Disorder, Harm Reduction, Health PromotionArmsPeer Intervention, Enhanced Usual Care
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
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  13. Naloxone's role in the national opioid crisis-past struggles, current efforts, and future opportunities.Translational research : the journal of laboratory and clinical medicine · 2021
    Review
  14. Review
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  17. Identifying Missed Clinical Opportunities in Delivery of Overdose Prevention and Naloxone Prescription to Adolescents Using Opioids.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

J Deanna Wilsona Division of General Pediatrics and Adolescent Medicine , Johns Hopkins University School of Medicine , Baltimore , Maryland , USA.
Natalie Spicyna Division of General Pediatrics and Adolescent Medicine , Johns Hopkins University School of Medicine , Baltimore , Maryland , USA.
Pamela Matsona Division of General Pediatrics and Adolescent Medicine , Johns Hopkins University School of Medicine , Baltimore , Maryland , USA.
Anika Alvanzob Division of General Internal Medicine , Johns Hopkins University School of Medicine , Baltimore , Maryland , USA.
Leonard Feldmana Division of General Pediatrics and Adolescent Medicine , Johns Hopkins University School of Medicine , Baltimore , Maryland , USA.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Adolescent Health Training ProgramT32HD052459 · NICHD · JOHNS HOPKINS UNIVERSITY · PI MARIA E. TRENT · 2006 to 2026
$4.0M
The Social Context of Adolescent Marijuana Use: A Systems ApproachK01DA035387 · NIDA · JOHNS HOPKINS UNIVERSITY · PI MATSON, PAMELA A · 2014 to 2018
$923k
NICHD NIH HHS T32 HD052459NIDA NIH HHS K01 DA035387
6 · The paper itself

Abstract

backgroundThe United States is facing an epidemic of opioid use and misuse leading to historically high rates of overdose. Community-based overdose education and naloxone distribution has effectively trained lay bystanders to recognize signs of overdose and administer naloxone for reversal. There has been a movement to encourage physicians to prescribe naloxone to all patients at risk of overdose; however, the rate of physician prescribing remains low. This study aims to describe resident knowledge of overdose risk assessment, naloxone prescribing practices, attitudes related to naloxone, and barriers to overdose prevention and naloxone prescription.

methodsThe HOPE (Hospital-based Overdose Prevention and Education) Initiative is an educational campaign to teach internal medicine residents to assess overdose risk, provide risk reduction counseling, and prescribe naloxone. As part of a needs assessment, internal medicine residents at an academic medical center in Baltimore, Maryland, were surveyed in 2015. Data were collected anonymously using Qualtrics.

resultsNinety-seven residents participated. Residents were overwhelmingly aware of naloxone (80%) and endorsed a willingness to prescribe (90%). Yet despite a high proportion of residents reporting patients in their panels at increased overdose risk (79%), few had prescribed naloxone (15%). Residents were willing to discuss overdose prevention strategies, although only a minority reported doing so (47%). The most common barriers to naloxone prescribing were related to knowledge gaps in how to prescribe and how to assess risk of overdose and identify candidates for naloxone (52% reporting low confidence in ability to identify patients who are at risk).

conclusionsMedicine residents are aware of naloxone and willing to prescribe it to at-risk patients. Due to decreased applied knowledge and limited self-efficacy, few residents have prescribed naloxone in the past. In order to improve rates of physician prescribing, initiatives must help physicians better assess risk of overdose and improve prescribing self-efficacy.

Indexed as

Health Knowledge, Attitudes, PracticeInternship and ResidencyAnalgesics, OpioidDrug OverdoseFemaleHealth Services AccessibilityHumansInternal MedicineMaleNaloxoneOpioid-Related DisordersProgram EvaluationAnalgesics, OpioidNaloxoneDrug overdosemedical educationnaloxone

Identifiers

PMID26820604
PMCPMC6400459
OpenAlexW2258331748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.