Evidence map›Paper›PMID 26820522›Full record

ArticleNeurotoxicology2016

Organophosphorus pesticide exposure and neurobehavioral performance in Latino children living in an orchard community.

Jaime Butler-Dawson, Kit Galvin, Peter S Thorne, Diane S Rohlman

Open access · greenAbstract read
In one paragraph

Article in Neurotoxicology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
15.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  9. Review
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  11. Article
  12. Construction of a ratiometric fluorescent sensing platform based on near-infrared carbon dots for organophosphorus pesticides detection.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Inhibition of Serum Esterases in Juvenile Rats Repeatedly Exposed to Low Levels of Chlorpyrifos.International journal of scientific research in environmental science and toxicology · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jaime Butler-DawsonDepartment of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, Iowa, United States.
Kit GalvinDepartment of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, Washington, United States.
Peter S ThorneDepartment of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, Iowa, United States.
Diane S RohlmanDepartment of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, Iowa, United States; Oregon Institute for Occupational Health Sciences, Oregon Health & Science University, Portland, OR, United States. Electronic address: diane-rohlman@uiowa.edu.
University of Iowa · USUniversity of Washington · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
Pacific Northwest Agricultural Safety and Health CenterU50OH007544 · OH · UNIVERSITY OF WASHINGTON · PI FENSKE, RICHARD ARNOLD · 2001 to 2010
$7.1M
NIEHS NIH HHS P30 ES005605NIOSH CDC HHS U50 OH007544
6 · The paper itself

Abstract

Children living in agricultural communities have a greater risk from pesticides due to para-occupational pathways. The goal of this study was to assess the impact of exposure to organophosphorus pesticides on the neurobehavioral performance of school-aged Latino children over time. Two exposure measures were used to estimate children's pesticide exposure: parent's occupation (agricultural or non-agricultural) and organophosphate residues in home carpet dust samples. During 2008-2011, 206 school-aged children completed a battery of neurobehavioral tests two times, approximately one year apart. The associations between both exposure measures and neurobehavioral performance were examined. Pesticide residues were detected in dust samples from both agricultural and non-agricultural homes, however, pesticides were detected more frequently and in higher concentrations in agricultural homes compared to non-agricultural homes. Although few differences were found between agricultural and non-agricultural children at both visits, deficits in learning from the first visit to the second visit, or less improvement, was found in agricultural children relative to non-agricultural children. These differences were significant for the Divided Attention and Purdue Pegboard tests. These findings are consistent with previous research showing deficits in motor function. A summary measure of organophosphate residues was not associated with neurobehavioral performance. Results from this study indicate that children in agricultural communities are at increased risk from pesticides as a result of a parent working in agricultural. Our findings suggest that organophosphate exposure may be associated with deficits in learning on neurobehavioral performance, particularly in tests of with motor function. In spite of regulatory phasing out of organophosphates in the U.S., we still see elevated levels and higher detection rates of several organophosphates in agricultural households than non-agricultural households, albeit lower levels than prior studies.

Indexed as

AgricultureEnvironmental ExposureAdolescentCase-Control StudiesChildChild, PreschoolFemaleHispanic or LatinoHumansLongitudinal StudiesMaleNeurodevelopmental DisordersNeurologic ExaminationNeuropsychological TestsOrganophosphate PoisoningSurveys and QuestionnairesChildren’s healthNeurobehavioral developmentOrganophosphate pesticide

Identifiers

PMID26820522
PMCPMC5223784
OpenAlexW2290390512

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.