ArticleEuropean journal of clinical pharmacology2016
Potentially inappropriate prescribing in two populations with differing socio-economic profiles: a cross-sectional database study using the PROMPT criteria.
Article in European journal of clinical pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Brief interventions targeting long-term benzodiazepine and Z-drug use in primary care: a systematic review and meta-analysis.Addiction (Abingdon, England) · 2020Pooled it
- Social disparities in patient safety in primary care: a systematic review.International journal for equity in health · 2018Pooled it
- Drug class duplication patterns among South African middle-aged adults: findings from a medicine claims database.International journal of clinical pharmacy · 2026Article
- Association between socioeconomic status and dispensing of higher-risk drug classes and polypharmacy in older community-based populations: a nationwide cohort study.European journal of clinical pharmacology · 2025Article
- Changes in benzodiazepine, z-drug, and other sedative prescribing in primary care in Ireland between 2014 and 2022.Family practice · 2025Article
- Patterns of Analgesic Prescribing and High-Risk Prescribing in Primary Care in Ireland 2014-2022-A Repeated Cross-Sectional Study.European journal of pain (London, England) · 2025Article
- Pharmacist-Led Interventions for Polypharmacy Management in Older Adults: A Systematic Review of Strategies and Outcomes in the United Kingdom and the Republic of Ireland.Pharmacy (Basel, Switzerland) · 2025Review
- Contribution of Potentially Inappropriate Medications to Polypharmacy-Associated Risk of Mortality in Middle-Aged Patients: A National Cohort Study.Journal of general internal medicine · 2024Observational
- Protocol for the development and validation of a Polypharmacy Assessment Score.Diagnostic and prognostic research · 2024Article
- Defining, identifying and addressing problematic polypharmacy within multimorbidity in primary care: a scoping review.BMJ open · 2024Article
- Potentially inappropriate prescribing in older adults with cancer receiving specialist palliative care: a retrospective observational study.International journal of clinical pharmacy · 2023Observational
- Data Resource Profile: The Enhanced Prescribing Database (EPD) in Northern Ireland.International journal of population data science · 2023Article
- The use of postal audit and feedback among Irish General Practitioners for the self - management of antimicrobial prescribing: a qualitative study.BMC primary care · 2022Article
- Residential Area Socioeconomic Deprivation is Associated with Physical Dependency and Polypharmacy in Community-Dwelling Older Adults: An Analysis of Health Administrative Data in Ireland.Journal of multidisciplinary healthcare · 2022Article
- Prevalence and predictors of potentially inappropriate prescribing in middle-aged adults: a repeated cross-sectional study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Article
- Trends in polypharmacy and potentially inappropriate medication (PIM) in older and middle-aged people treated for diabetes.British journal of clinical pharmacology · 2021Article
- An Update on Medication Use in Older Adults: a Narrative Review.Current epidemiology reports · 2021Review
- The Burden of Potentially Inappropriate Medications in Chronic Polypharmacy.Journal of clinical medicine · 2020Article
- Prevalence of potentially inappropriate medications in older adults in Argentina using Beers criteria and the IFAsPIAM List.International journal of clinical pharmacy · 2019Observational
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Authors and funding
11 authors.
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Abstract
purposeThe purpose of this study is to establish the prevalence of potentially inappropriate prescribing (PIP) in middle-aged adults (45-64 years) in two populations with differing socio-economic profiles, and to investigate factors associated with PIP, using the PROMPT (PRescribing Optimally in Middle-aged People's Treatments) criteria.
methodsA retrospective cross-sectional study was conducted using 2012 data from the Enhanced Prescribing Database (EPD), covering the full population in Northern Ireland and the Health Services Executive Primary Care Reimbursement Service (HSE-PCRS) database, covering the most socio-economically deprived third of the population in this age group in the Republic of Ireland. The prevalence for each PROMPT criterion and overall prevalence of PIP were calculated. Logistic regression was used to investigate the association between PIP and gender, age group and polypharmacy.
resultsThis study included 441,925 patients from the EPD and 309,748 patients from the HSE-PCRS database. Polypharmacy was common in both datasets (46.7 % in the HSE-PCRS and 20.3 % in the EPD). The prevalence of PIP was 42.9 % (95%CI 42.7, 43.1) in the HSE-PCRS and 21.1 % (95%CI 21.0, 21.2) in the EPD. Age group, female gender and polypharmacy were significantly associated with PIP in both populations (p < 0.05) and polypharmacy had the strongest association.
conclusionsPIP is common amongst middle-aged people with the risk of PIP increasing with polypharmacy. Differences in the prevalence of polypharmacy and PIP between the two populations may relate to heterogeneity in healthcare services and different socio-economic profiles, with higher rates of multimorbidity and associated polypharmacy in more deprived groups.
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