Evidence map›Paper›PMID 26819872›Full record

ArticleMass spectrometry (Tokyo, Japan)2014

Peptide Peak Detection for Low Resolution MALDI-TOF Mass Spectrometry.

Jingwen Yao, Shin-Ichi Utsunomiya, Shigeki Kajihara, Tsuyoshi Tabata, Ken Aoshima, Yoshiya Oda, Koichi Tanaka

Abstract read
In one paragraph

Article in Mass spectrometry (Tokyo, Japan), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jingwen YaoKoichi Tanaka Laboratory of Advanced Science and Technology, Shimadzu Corporation.
Shin-Ichi UtsunomiyaKoichi Tanaka Laboratory of Advanced Science and Technology, Shimadzu Corporation.
Shigeki KajiharaKoichi Tanaka Laboratory of Advanced Science and Technology, Shimadzu Corporation.
Tsuyoshi TabataBiomarker & Personalized Medicine, Eisai Product Creation Systems.
Ken AoshimaBiomarker & Personalized Medicine, Eisai Product Creation Systems.
Yoshiya OdaBiomarker & Personalized Medicine, Eisai Product Creation Systems.
Koichi TanakaKoichi Tanaka Laboratory of Advanced Science and Technology, Shimadzu Corporation.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new peak detection method has been developed for rapid selection of peptide and its fragment ion peaks for protein identification using tandem mass spectrometry. The algorithm applies classification of peak intensities present in the defined mass range to determine the noise level. A threshold is then given to select ion peaks according to the determined noise level in each mass range. This algorithm was initially designed for the peak detection of low resolution peptide mass spectra, such as matrix-assisted laser desorption/ionization Time-of-Flight (MALDI-TOF) mass spectra. But it can also be applied to other type of mass spectra. This method has demonstrated obtaining a good rate of number of real ions to noises for even poorly fragmented peptide spectra. The effect of using peak lists generated from this method produces improved protein scores in database search results. The reliability of the protein identifications is increased by finding more peptide identifications. This software tool is freely available at the Mass++ home page (http://www.first-ms3d.jp/english/achievement/software/).

Indexed as

matrix-assisted laser desorption/ionizationpeak detectionpeptide identificationtandem mass spectrometry

Identifiers

PMID26819872
PMCPMC4306743

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.