Evidence map›Paper›PMID 26819830›Full record

ArticleBiomedical optics express2016

Time-resolved singlet-oxygen luminescence detection with an efficient and practical semiconductor single-photon detector.

Gianluca Boso, Damei Ke, Boris Korzh, Jordan Bouilloux, Norbert Lange, Hugo Zbinden

Abstract read
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gianluca BosoGroup of Applied Physics, University of Geneva, Chemin de Pinchat 22, Genève 4, CH-1211, Switzerland.
Damei KeSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Quai Ernest Ansermet 30, Genève 4, CH-1211, Switzerland.
Boris KorzhGroup of Applied Physics, University of Geneva, Chemin de Pinchat 22, Genève 4, CH-1211, Switzerland.
Jordan BouillouxSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Quai Ernest Ansermet 30, Genève 4, CH-1211, Switzerland.
Norbert LangeSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Quai Ernest Ansermet 30, Genève 4, CH-1211, Switzerland.
Hugo ZbindenGroup of Applied Physics, University of Geneva, Chemin de Pinchat 22, Genève 4, CH-1211, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In clinical applications, such as PhotoDynamic Therapy, direct singlet-oxygen detection through its luminescence in the near-infrared range (1270 nm) has been a challenging task due to its low emission probability and the lack of suitable single-photon detectors. Here, we propose a practical setup based on a negative-feedback avalanche diode detector that is a viable alternative to the current state-of-the art for different clinical scenarios, especially where geometric collection efficiency is limited (e.g. fiber-based systems, confocal microscopy, scanning systems etc.). The proposed setup is characterized with Rose Bengal as a standard photosensitizer and it is used to measure the singlet-oxygen quantum yield of a new set of photosensitizers for site-selective photodynamic therapy.

Indexed as

(030.5260) Photon counting(170.3880) Medical and biological imaging(170.5180) Photodynamic therapy(170.6280) Spectroscopy, fluorescence and luminescence(170.6920) Time-resolved imaging(230.5160) Photodetectors(250.5230) Photoluminescence(270.5570) Quantum detectors(350.5130) Photochemistry

Identifiers

PMID26819830
PMCPMC4722905

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.