ArticleBiomedical optics express2016
Differentiation of cutaneous melanoma from surrounding skin using laser-induced breakdown spectroscopy.
Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The trial behind it
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Who cites it
18 citing papers in PubMed, 64 citations in OpenAlex.
- Influence of Sample Preparation Methods for Porcine Tissue: Calibration-Free LIBS for In Vivo Applications.Journal of biophotonics · 2026Article
- From Fundamentals of Laser-Induced Breakdown Spectroscopy to Recent Advancements in Cancer Detection and Calcified Tissues Analysis: An Overview (2015-2025).Molecules (Basel, Switzerland) · 2025Review
- Laser-induced breakdown spectroscopy for lithium-mediated cancer cell detection and ablation.Lasers in medical science · 2025Article
- Fusion of laser-induced breakdown spectroscopy technology and deep learning: a new method to identify malignant and benign lung tumors with high accuracy.Analytical and bioanalytical chemistry · 2024Article
- Identification of tumor tissue in thin pathological samples via femtosecond laser-induced breakdown spectroscopy and machine learning.Scientific reports · 2023Article
- Rapid Test for Adulteration of Fritillaria Thunbergii in Fritillaria Cirrhosa by Laser-Induced Breakdown Spectroscopy.Foods (Basel, Switzerland) · 2023Article
- Discrimination of normal and cancerous human skin tissues based on laser-induced spectral shift fluorescence microscopy.Scientific reports · 2022Article
- Predictive data clustering of laser-induced breakdown spectroscopy for brain tumor analysis.Biomedical optics express · 2021Article
- Diagnosis and staging of multiple myeloma using serum-based laser-induced breakdown spectroscopy combined with machine learning methods.Biomedical optics express · 2021Article
- Machine learning-based LIBS spectrum analysis of human blood plasma allows ovarian cancer diagnosis.Biomedical optics express · 2021Article
- Primary study of identification of parathyroid gland based on laser-induced breakdown spectroscopy.Biomedical optics express · 2021Article
- Methodology for the Implementation of Internal Standard to Laser-Induced Breakdown Spectroscopy Analysis of Soft Tissues.Sensors (Basel, Switzerland) · 2021Article
- Blood cancer diagnosis using ensemble learning based on a random subspace method in laser-induced breakdown spectroscopy.Biomedical optics express · 2020Article
- Combined Nd:YAG and Er:YAG lasers for real-time closed-loop tissue-specific laser osteotomy.Biomedical optics express · 2020Article
- Mapping of cutaneous melanoma by femtosecond laser-induced breakdown spectroscopy.Journal of biomedical optics · 2018Article
- Identification of cervical cancer using laser-induced breakdown spectroscopy coupled with principal component analysis and support vector machine.Lasers in medical science · 2018Article
- Discrimination of lymphoma using laser-induced breakdown spectroscopy conducted on whole blood samples.Biomedical optics express · 2018Article
- Elemental analysis of tissue pellets for the differentiation of epidermal lesion and normal skin by laser-induced breakdown spectroscopy.Biomedical optics express · 2016Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laser-induced breakdown spectroscopy (LIBS) has the potential to be used as a surgical tool for simultaneous tissue ablation and elemental analysis of the ablated tissue. LIBS may be used to distinguish melanoma lesions from the surrounding dermis based on the quantitative difference of elements within melanoma lesions. Here, we measured the elements in homogenized pellets and real tissues from excised skin samples of melanoma-implanted mice. In addition, statistical analysis of LIBS spectra using principal component analysis and linear discriminant analysis was performed. Our results showed that this method had high detection sensitivity, highlighting the potential of this tool in clinical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.