ArticleBiomedical optics express2016
Retinal nerve fiber layer reflectometry must consider directional reflectance.
Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Predicting perimetric defects from en face maps of retinal nerve fibre layer reflectance.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2024Article
- Multifunctional adaptive optics optical coherence tomography allows cellular scale reflectometry, polarimetry, and angiography in the living human eye.Biomedical optics express · 2024Article
- Targeted spectroscopy in the eye fundus.Journal of biomedical optics · 2023Article
- Depth-resolved extraction of optical attenuation for glaucoma assessment in clinical settings: a pilot study.Biomedical optics express · 2022Article
- Adaptive optics scanning laser ophthalmoscopy may support early diagnosis of glaucoma.Indian journal of ophthalmology · 2022Article
- Enhanced Objective Detection of Retinal Nerve Fiber Bundle Defects in Glaucoma With a Novel Method for En Face OCT Slab Image Construction and Analysis.Translational vision science & technology · 2021Article
- A Simple Subjective Evaluation of Enface OCT Reflectance Images Distinguishes Glaucoma From Healthy Eyes.Translational vision science & technology · 2021Article
- Early localized alterations of the retinal inner plexiform layer in association with visual field worsening in glaucoma patients.PloS one · 2021Article
- A Reflectivity Measure to Quantify Bruch's Membrane Calcification in Patients with Pseudoxanthoma Elasticum Using Optical Coherence Tomography.Translational vision science & technology · 2020Article
- Temporal change of retinal nerve fiber layer reflectance speckle in normal and hypertensive retinas.Experimental eye research · 2019Article
- Changes in fundus reflectivity during myopia development in chickens.Biomedical optics express · 2019Article
- Time-resolved quantitative inter-eye comparison of cardiac cycle-induced blood volume changes in the human retina.Biomedical optics express · 2018Article
- Evaluating glaucomatous abnormality in peripapillary optical coherence tomography enface visualisation of the retinal nerve fibre layer reflectance.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2018Article
- Response of the Retinal Nerve Fiber Layer Reflectance and Thickness to Optic Nerve Crush.Investigative ophthalmology & visual science · 2018Article
- Novel Technique for Quantifying Retinal Nerve Fiber Bundle Abnormality in the Temporal Raphe.Optometry and vision science : official publication of the American Academy of Optometry · 2018Article
- Multi-directional optical coherence tomography for retinal imaging.Biomedical optics express · 2017Article
- Reflectance Spectrum and Birefringence of the Retinal Nerve Fiber Layer With Hypertensive Damage of Axonal Cytoskeleton.Investigative ophthalmology & visual science · 2017Article
- Biological aspects of axonal damage in glaucoma: A brief review.Experimental eye research · 2017Review
- Changes in Retinal Nerve Fiber Layer Reflectance Intensity as a Predictor of Functional Progression in Glaucoma.Investigative ophthalmology & visual science · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Recent studies reveal that measurements of retinal nerve fiber layer (RNFL) reflectance provide more sensitive detection of glaucomatous damage than RNFL thickness, but most do not consider directional reflectance of the RNFL, an important source of variability. This study quantitatively compared RNFL directional reflectance, represented by an angular spread function (ASF), measured at different scattering angles, different wavelengths and different distances from the optic nerve head (ONH) and for bundles with different thicknesses (T). An ASF was characterized by its amplitude (A) and width (W). Internal reflectance of a bundle was expressed as A/T. The study found that A varied significantly with scattering angle and wavelength and that A/T was different among bundles but constant along the same bundle, indicating that the internal structure of axons may vary among bundles but does not change with distance. This study also found that W was larger near the ONH and at longer wavelengths, but did not depend on scattering angle or T. Because a 4.3° change in incident angle can change reflected intensity by a factor of 2.7, accounting for directional reflectance should improve the accuracy and reproducibility of RNFL reflectance measurements.
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Registered trials
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