ReviewWorld journal of gastroenterology2016
Diagnosing gastrointestinal illnesses using fecal headspace volatile organic compounds.
Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Diagnostic performance of volatile organic compounds analysis and electronic noses for detecting colorectal cancer: a systematic review and meta-analysis.Frontiers in oncology · 2024Pooled it
- Development of a rapid metal oxide semiconductor-based sensory system for noninvasive neonatal sepsis detection.Mikrochimica acta · 2026Article
- Innovative use ofFrontiers in veterinary science · 2026Article
- Non-Invasive Monitoring and Differentiation of Aging Mice Treated with Goat Whey Powder by an Electronic Nose Coupled with Chemometric Methods.Sensors (Basel, Switzerland) · 2025Article
- The role of intestinal gases in pediatric functional constipation: a narrative review of pathophysiology and emerging therapeutics.Frontiers in nutrition · 2025Review
- Gas Chromatography-Sensor System Aids Diagnosis of Inflammatory Bowel Disease, and Separates Crohn's from Ulcerative Colitis, in Children.Sensors (Basel, Switzerland) · 2024Article
- The epithelialProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Wake up and smell the coffee: The potential of faecal volatile organic compounds in paediatric inflammatory bowel disease.United European gastroenterology journal · 2024Article
- Faecal volatile organic compounds differ according to inflammatory bowel disease sub-type, severity, and response to treatment in paediatric patients.United European gastroenterology journal · 2024Article
- Non-Invasive Blood Pressure Tracking of Spontaneous Hypertension Rats Using an Electronic Nose.Sensors (Basel, Switzerland) · 2023Article
- Volatile Organic Compound Assessment as a Screening Tool for Early Detection of Gastrointestinal Diseases.Microorganisms · 2023Review
- Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice.Scientific reports · 2023Article
- Expanding beyond endoscopy: A review of non-invasive modalities in Barrett's esophagus screening and surveillance.World journal of gastroenterology · 2022Review
- Bile-volatile organic compounds in the diagnostics of pancreatic cancer and biliary obstruction: A prospective proof-of-concept study.Frontiers in oncology · 2022Article
- Volatile organic compound profiling as a potential biomarker in irritable bowel syndrome: A feasibility study.Frontiers in medicine · 2022Article
- Monitoring the Reaction of the Body State to Antibiotic Treatment againstMolecules (Basel, Switzerland) · 2021Article
- Analyses of short-chain fatty acids and exhaled breath volatiles in dietary intervention trials for metabolic diseases.Experimental biology and medicine (Maywood, N.J.) · 2021Article
- The Effects of Prebiotic Supplementation with OMNi-LOGiCNutrients · 2020Article
- Multisensor Systems and Arrays for Medical Applications Employing Naturally-Occurring Compounds and Materials.Sensors (Basel, Switzerland) · 2020Review
- Smell - Adding a New Dimension to Urinalysis.Biosensors · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Volatile organic compounds (VOCs) emitted from stool are the components of the smell of stool representing the end products of microbial activity and metabolism that can be used to diagnose disease. Despite the abundance of hydrogen, carbon dioxide, and methane that have already been identified in human flatus, the small portion of trace gases making up the VOCs emitted from stool include organic acids, alcohols, esters, heterocyclic compounds, aldehydes, ketones, and alkanes, among others. These are the gases that vary among individuals in sickness and in health, in dietary changes, and in gut microbial activity. Electronic nose devices are analytical and pattern recognition platforms that can utilize mass spectrometry or electrochemical sensors to detect these VOCs in gas samples. When paired with machine-learning and pattern recognition algorithms, this can identify patterns of VOCs, and thus patterns of smell, that can be used to identify disease states. In this review, we provide a clinical background of VOC identification, electronic nose development, and review gastroenterology applications toward diagnosing disease by the volatile headspace analysis of stool.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.