Evidence map›Paper›PMID 26819505›Full record

ReviewWorld journal of gastroenterology2016

Liver pathology of hepatitis C, beyond grading and staging of the disease.

Sadhna Dhingra, Stephen C Ward, Swan N Thung

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Observational
  13. Article
  14. Gd-EOB-DTPA DCE-MRI biomarkers in a rabbit model of liver fibrosis.American journal of translational research · 2018
    Article
  15. Article
  16. Article
  17. Hepatitis C virus: Promising discoveries and new treatments.World journal of gastroenterology · 2016
    Review
  18. Diagnostic and prognostic significance of hepatic steatosis in patients with chronic hepatitis C.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sadhna DhingraSadhna Dhingra, Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, United States.
Stephen C WardSadhna Dhingra, Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, United States.
Swan N ThungSadhna Dhingra, Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver biopsy evaluation plays a critical role in management of patients with viral hepatitis C. In patients with acute viral hepatitis, a liver biopsy, though uncommonly performed, helps to rule out other non-viral causes of deranged liver function. In chronic viral hepatitis C, it is considered the gold standard in assessment of the degree of necroinflammation and the stage of fibrosis, to help guide treatment and determine prognosis. It also helps rule out any concomitant diseases such as steatohepatitis, hemochromatosis or others. In patients with chronic progressive liver disease with cirrhosis and dominant nodules, a targeted liver biopsy is helpful in differentiating a regenerative nodule from dysplastic nodule or hepatocellular carcinoma. In the setting of transplantation, the liver biopsy helps distinguish recurrent hepatitis C from acute rejection and also is invaluable in the diagnosis of fibrosing cholestatic hepatitis, a rare variant of recurrent hepatitis C. This comprehensive review discusses the entire spectrum of pathologic findings in the course of hepatitis C infection.

Indexed as

Antiviral AgentsBiopsyDiagnosis, DifferentialDisease ProgressionHepatitis C, ChronicHumansLiverLiver TransplantationPredictive Value of TestsSeverity of Illness IndexTreatment OutcomeAntiviral AgentsBiopsyGradingHepatitis CLiver pathologyNeoplasiaStaging

Identifiers

PMID26819505
PMCPMC4721971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.