Evidence map›Paper›PMID 26819055›Full record

ArticleHaematologica2016

Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effect after allogeneic hematopoietic cell transplantation.

Brian G Engelhardt, Sophie Paczesny, Dae Kwang Jung, Etienne Daguindau, Madan Jagasia, Bipin N Savani, Wichai Chinratanalab, Robert F Cornell, Stacey Goodman, John P Greer and 5 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Brian G EngelhardtDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Sophie PaczesnyDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA Department of Microbiology and Immunology, Indiana University School, Indianapolis, IN, USA.
Dae Kwang JungDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Etienne DaguindauDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA Department of Microbiology and Immunology, Indiana University School, Indianapolis, IN, USA.
Madan JagasiaDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Bipin N SavaniDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Wichai ChinratanalabDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Robert F CornellDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Stacey GoodmanDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
John P GreerDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Adetola A KassimDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Salyka SengsayadethDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Sandra M YoderDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Michael T RockDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
James E CroweDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA Department of Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA james.crowe@vanderbilt.edu.

Funding

Translating Novel Drug-Targetable Biomarkers to Treat Graft versus Host DiseaseR01CA168814 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PACZESNY, SOPHIE · 2013 to 2024
$3.0M
Metabolic and CD4+ T Cell Dysregulation in Post-Transplant Diabetes MellitusK23HL122143 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ENGELHARDT, BRIAN G · 2014 to 2016
$402k
NCI NIH HHS R01 CA168814NHLBI NIH HHS K23 HL122143
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hematopoietic Stem Cell TransplantationImmune ToleranceImmunity, CellularLeukemiaAdultAgedAllograftsFemaleGraft vs Leukemia EffectHumansMaleMiddle AgedTh1 Cellsallogeneic hematopoietic cell transplantationearly Th1 immunitygraft-versus-leukemia effectimmune tolerance

Identifiers

PMID26819055
PMCPMC5004357

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.