ArticleScientific reports2016
Length Distribution of Ancestral Tracks under a General Admixture Model and Its Applications in Population History Inference.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Recent advances in methods to characterize archaic introgression in modern humans.Genome research · 2026Review
- Reconstructing complex admixture history using a hierarchical model.Briefings in bioinformatics · 2024Article
- Temporal Variation in Introgressed Segments' Length Statistics Computed from a Limited Number of Ancient Genomes Sheds Light on Past Admixture Pulses.Molecular biology and evolution · 2023Article
- Human genetic admixture through the lens of population genomics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- An Extended Admixture Pulse Model Reveals the Limitations to Human-Neandertal Introgression Dating.Molecular biology and evolution · 2021Article
- Tracing the Genetic Legacy of the Tibetan Empire in the Balti.Molecular biology and evolution · 2021Article
- Assortative mating by population of origin in a mechanistic model of admixture.Theoretical population biology · 2020Article
- Dating admixture events is unsolved problem in multi-way admixed populations.Briefings in bioinformatics · 2020Article
- AdmixSim: A Forward-Time Simulator for Various Complex Scenarios of Population Admixture.Frontiers in genetics · 2020Article
- The spatial scale of dispersal revealed by admixture tracts.Evolutionary applications · 2019Article
- MultiWaver 2.0: modeling discrete and continuous gene flow to reconstruct complex population admixtures.European journal of human genetics : EJHG · 2019Article
- Loter: A Software Package to Infer Local Ancestry for a Wide Range of Species.Molecular biology and evolution · 2018Article
- Article
- Modeling Continuous Admixture Using Admixture-Induced Linkage Disequilibrium.Scientific reports · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The length of ancestral tracks decays with the passing of generations which can be used to infer population admixture histories. Previous studies have shown the power in recovering the histories of admixed populations via the length distributions of ancestral tracks even under simple models. We believe that the deduction of length distributions under a general model will greatly elevate the power. Here we first deduced the length distributions under a general model and proposed general principles in parameter estimation and model selection with the deduced length distributions. Next, we focused on studying the length distributions and its applications under three typical special cases. Extensive simulations showed that the length distributions of ancestral tracks were well predicted by our theoretical framework. We further developed a new method, AdmixInfer, based on the length distributions and good performance was observed when it was applied to infer population histories under the three typical models. Notably, our method was insensitive to demographic history, sample size and threshold to discard short tracks. Finally, good performance was also observed when applied to some real datasets of African Americans, Mexicans and South Asian populations from the HapMap project and the Human Genome Diversity Project.
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