Evidence map›Paper›PMID 26818847›Full record

Trial reportBMC neurology2016

Effects on mobility training and de-adaptations in subjects with Spinal Cord Injury due to a Wearable Robot: a preliminary report.

Patrizio Sale, Emanuele Francesco Russo, Michele Russo, Stefano Masiero, Francesco Piccione, Rocco Salvatore Calabrò, Serena Filoni

3 registry-linked trialsOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in BMC neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 36 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 9 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02065830 naterminatednot on this map

ROBOticsSpinalCordInjuryEKSO: Outdoor and Indoor Mobility in People With SCI.

TypeinterventionalSponsorIRCCS San Raffaele RomaRan2014 to 2016Enrolled30ConditionsSpinal Cord InjuryArmsEKSO
NCT02943915 nacompletednot on this map

The WISE Trial - Walking Improvement for SCI With Exoskeleton

TypeinterventionalSponsorEkso BionicsRan2016 to 2019Enrolled45ConditionsInjuries, Spinal CordArmsEkso GT Rehabilitation Therapy, Body Weight Supported (BWS) Treadmill Training
NCT03805009 nacompletednot on this map

Efficacy of End-Effector Robot-Assisted Gait Training in Subacute Stroke Patients: Clinical and Gait Outcomes

TypeinterventionalSponsorIRCCS San Raffaele RomaRan2013 to 2018Enrolled26ConditionsSevere Stroke, Acute Stroke, Mild Stroke, Central Nervous System DiseasesArmsRobot-Assisted Gait Training (RAGT)
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 9 syntheses or guidelines pooled it, 79 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Patrizio SaleDepartment of Neurorehabilitation, I.R.C.C.S. San Camillo Hospital, via Alberoni 70, 30126, Venice, Italy. patrizio.sale@gmail.com.
Emanuele Francesco RussoFondazione Centri di Riabilitazione Padre Pio Onlus, San Giovanni Rotondo, Foggia, Italy.
Michele RussoFondazione Centri di Riabilitazione Padre Pio Onlus, San Giovanni Rotondo, Foggia, Italy.
Stefano MasieroDepartment of Neuroscience, Rehabilitation Unit, University of Padua, Via Giustiniani 2, Padua, 35128, Italy.
Francesco PiccioneDepartment of Neurorehabilitation, I.R.C.C.S. San Camillo Hospital, via Alberoni 70, 30126, Venice, Italy.
Rocco Salvatore CalabròNeurobehavioral and Robotic Neurorehabilitation Laboratory Coordinator IRCCS Centro, Neurolesi "Bonino-Pulejo" Messina, Messina, Italy.
Serena FiloniFondazione Centri di Riabilitazione Padre Pio Onlus, San Giovanni Rotondo, Foggia, Italy.
IRCCS San Camillo Hospital · ITCentro Neurolesi Bonino Pulejo · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpinal cord injury (SCI) is a severe neurological disorder associated not only with ongoing medical complications but also with a significant loss of mobility and participation. The introduction of robotic technologies to recover lower limb function has been greatly employed in the rehabilitative practice. The aim of this preliminary report were to evaluate the efficacy, the feasibility and the changes in the mobility and in the de-adaptations of a new rehabilitative protocol for EKSO™ a robotic exoskeleton device in subjects with SCI disease with an impairment of lower limbs assessed by gait analysis and clinical outcomes.

methodThis is a pilot single case experimental A-B (pre-post) design study. Three cognitively intact voluntary participants with SCI and gait disorders were admitted. All subjects were submitted to a training program of robot walking sessions for 45 min daily over 20 sessions. The spatiotemporal parameters at the beginning (T0) and at the end of treatment (T1) were recorded. Other clinical assessments (6 min walking test and Timed Up and Go test) were acquired at T0 and T1.

resultsRobot training were feasible and acceptable and all participants completed the training sessions. All subjects showed improvements in gait spatiotemporal indexes (Mean velocity, Cadence, Step length and Step width) and in 6 min Walking Test (T0 versus T1).

conclusionsRobot training is a feasible form of rehabilitation for people with SCI. Further investigation regarding long term effectiveness of robot training in time is necessary.

trial registrationClinicalTrials.gov NCT02065830.

Indexed as

Adaptation, PhysiologicalAdultExercise TestFeasibility StudiesFemaleGait Disorders, NeurologicHumansMaleMiddle AgedPhysical Therapy ModalitiesPilot ProjectsRoboticsSpinal Cord InjuriesYoung Adult

Identifiers

PMID26818847
PMCPMC4730780
OpenAlexW2254769129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.