ArticleJournal of physiological anthropology2016
Hemoglobin as a possible biochemical index of hypertension-induced vascular damage.
Article in Journal of physiological anthropology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Factors influencing new-onset hypertension in elderly patients with obstructive sleep apnea: A multicenter cohort study.Clinical and translational science · 2023Article
- Article
- Influence of height on endothelial maintenance activity: a narrative review.Environmental health and preventive medicine · 2021Review
- Risk factors of the progression to hypertension and characteristics of natural history during progression: A national cohort study.PloS one · 2020Article
- Short stature-related single-nucleotide polymorphism (SNP) activates endothelial repair activity in elderly Japanese.Environmental health and preventive medicine · 2019Article
- Association of hemoglobin concentration with handgrip strength in relation to hepatocyte growth factor levels among elderly Japanese men aged 60-69 years: a cross-sectional study.Environmental health and preventive medicine · 2018Article
- Hepatocyte growth factor and carotid intima-media thickness in relation to circulating CD34-positive cell levels.Environmental health and preventive medicine · 2018Article
- Possible mechanism underlying the association between height and vascular remodeling in elderly Japanese men.Oncotarget · 2018Article
- Evaluation of lipid profiles and hematological parameters in hypertensive patients: Laboratory-based cross-sectional study.SAGE open medicine · 2018Article
- Association between high-density lipoprotein-cholesterol and hypertension in relation to circulating CD34-positive cell levels.Journal of physiological anthropology · 2017Article
- Article
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Authors and funding
10 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWe previously reported on the positive association of hemoglobin with hypertension and atherosclerosis. On the other hand, hepatocyte growth factor (HGF) has been evaluated as a possible biochemical index of hypertension-induced vascular damage. However, no studies have reported on a correlation between hemoglobin and HGF accounting for hypertension status.
methodsA cross-sectional study of 1108 subjects (392 men and 716 women, 40-93 years old) who were undergoing a general checkup in 2014 was conducted.
resultsMultiple linear regression analysis adjustment for known cardiovascular risk factors showed no significant correlation between hemoglobin and HGF in non-hypertensive subjects, but a significant positive correlation in hypertensive subjects; β (parameter estimate) = 0.3 (p = 0.975) for non-hypertensive men, β = 0.4 (p = 0.925) for non-hypertensive women, β = 32.7 (p < 0.001) for hypertensive men, and β = 18.7 (p = 0.002) for hypertensive women.
conclusionWe found a significant positive correlation between hemoglobin and HGF among hypertensive men and women. Like HGF, hemoglobin may be a useful indicator to evaluate hypertension-induced vascular damage. Since hemoglobin can easily be measured, these results support hemoglobin as an efficient tool to evaluate vascular damage induced by hypertension in daily medical practice.
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