Evidence map›Paper›PMID 26818604›Full record

Trial reportNutrition journal2016

Post-prandial glucose and insulin responses of hummus alone or combined with a carbohydrate food: a dose-response study.

Livia S A Augustin, Laura Chiavaroli, Janice Campbell, Adish Ezatagha, Alexandra L Jenkins, Amin Esfahani, Cyril W C Kendall

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrition journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  11. Phase 1 Study of the Pharmacology of BTI320 Before High-Glycemic Meals.Clinical pharmacology in drug development · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Livia S A AugustinClinical Nutrition and Risk Factor Modification Center, St. Michael's Hospital, Toronto, ON, Canada.
Laura ChiavaroliGlycemic Index Laboratories Inc., Toronto, ON, Canada.
Janice CampbellGlycemic Index Laboratories Inc., Toronto, ON, Canada.
Adish EzataghaGlycemic Index Laboratories Inc., Toronto, ON, Canada.
Alexandra L JenkinsGlycemic Index Laboratories Inc., Toronto, ON, Canada.
Amin EsfahaniSchool of Medicine, New York Medical College, Valhalla, NY, USA.
Cyril W C KendallGlycemia Consulting, 32 Ridley Gardens, Toronto, ON, M6R 2T8, Canada. cyril.kendall@utoronto.ca.
Glycemic Index Laboratories · CANew York Medical College · USSt. Michael's Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPulses are low glycemic index (GI) foods and have been associated with reduced risk of heart disease, diabetes and some cancers. However the blood glucose and insulin responses of hummus, a food containing chickpea, have not been thoroughly tested.

methodsTen healthy subjects each consumed 11 breakfast study meals in randomized order over a period of 15 weeks. Hummus was consumed alone at three doses (2.7 g, 10.8 g and 25 g available carbohydrate [avCHO] portions) and with 50 g avCHO from white bread at three doses (2.7 g, 5.4 g and 10.8 g avCHO portions). The responses elicited by hummus alone were compared with 25 g avCHO portions of white bread, while those after hummus plus white bread were compared with 50 g avCHO from white bread. Plasma glucose and serum insulin responses were monitored over two hours and the GI and insulin index (II) calculated using standard methodology.

resultsThe GI and II of hummus were 15 ± 3 and 52 ± 13, respectively, and were significantly lower than white bread (P < 0.05). The glucose and insulin incremental area under the curve (IAUC) for hummus alone were significantly lower than white bread except for insulin IAUC of hummus 25 g avCHO. The peak rise of blood glucose and insulin after hummus were significantly lower than after white bread. Glucose and insulin IAUC after adding hummus to bread did not differ significantly from white bread alone. However the blood glucose 45 min after adding 25 g avCHO from hummus to white bread was significantly lower while at 120 min it was significantly higher than after white bread alone.

conclusionsThis study demonstrated that, similar to chickpeas, hummus has a very low GI and II. Postprandial glucose responses were 4 times less than that of white bread and did not compromise insulin levels.

Indexed as

Postprandial PeriodAdolescentAdultBlood GlucoseBody Mass IndexCross-Over StudiesDietary CarbohydratesFemaleGlycemic IndexHumansInsulinMaleMealsMiddle AgedYoung AdultBlood GlucoseDietary CarbohydratesInsulin

Identifiers

PMID26818604
PMCPMC4730744
OpenAlexW2271777510

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.