Evidence map›Paper›PMID 26818474›Full record

ArticleAddiction science & clinical practice2016

Management of patients with issues related to opioid safety, efficacy and/or misuse: a case series from an integrated, interdisciplinary clinic.

William C Becker, Jessica S Merlin, Ajay Manhapra, Ellen L Edens

Open access · goldAbstract read
In one paragraph

Article in Addiction science & clinical practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. French-Canadian Translation and Cultural Adaptation of the Clinical Opiate Withdrawal Scale: The COWS-FC.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

William C BeckerVA Connecticut Healthcare System, 950 Campbell Avenue, Mail Stop 151B, West Haven, CT, 06516, USA. william.becker@yale.edu.
Jessica S MerlinUniversity of Alabama at Birmingham, BBRB 220a, 1720 2nd Avenue South, Birmingham, AL, 35233, USA. jessicasarahmerlin@gmail.com.
Ajay ManhapraVA Connecticut Healthcare System, 950 Campbell Avenue, Mail Stop 151B, West Haven, CT, 06516, USA. ajay.manhapra@yale.edu.
Ellen L EdensVA Connecticut Healthcare System, 950 Campbell Avenue, Mail Stop 151B, West Haven, CT, 06516, USA. ellen.edens@yale.edu.
VA Connecticut Healthcare System · USUniversity of Alabama at Birmingham · USYale University · US

Funding

Development of a Behavioral Intervention for Chronic Pain in Individuals with HIVK23MH104073 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MERLIN, JESSICA S · 2015 to 2018
$732k
NIMH NIH HHS K23 MH104073NIMH NIH HHS K23MH104073-01A1
6 · The paper itself

Abstract

backgroundPatients, providers, communities and health systems have struggled to achieve balance between access to opioid treatment for chronic pain and its potential harmful consequences: especially misuse, addiction and overdose. We developed an interdisciplinary clinic embedded within primary care (the Opioid Reassessment Clinic-ORC) with the goal of improving the quality of care of patients with co-occurring chronic pain and issues related to opioid safety, efficacy and/or misuse. CASE DESCRIPTIONS: We present three cases referred to the ORC that highlight complex clinical scenarios related to assessment and treatment of patients with chronic pain and issues related to opioid safety, efficacy and misuse. DISCUSSION AND EVALUATION: In the context of the three cases, with respect to assessment, we discuss: making the diagnosis of opioid use disorder; allowing the patient space to endorse lack of efficacy; identification of co-occurring hazardous alcohol use; and recognizing barriers to multimodal pain care. With respect to treatment, we discuss: making a change in treatment with which the patient may not agree; effectiveness of buprenorphine/naloxone for the treatment of chronic pain; responding to low efficacy; and making continued opioid therapy contingent on engagement with substance abuse treatment.

conclusionsThe core components of our approach-biopsychosocial assessment and multimodal treatment planning with an emphasis on promoting functional goals and safety using clear communication and a patient-centered stance-should guide providers in the management of similar clinical scenarios. More evidence is needed to definitively guide specific interventions and points of clinical equipoise.

Indexed as

AlcoholismAnalgesics, OpioidBuprenorphine, Naloxone Drug CombinationChronic PainHumansOpioid-Related DisordersPain ManagementPrimary Health CareQuality ImprovementAnalgesics, OpioidBuprenorphine, Naloxone Drug Combination

Identifiers

PMID26818474
PMCPMC4730605
OpenAlexW2260227685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.