ArticleVirulence2016
Host derived biomarkers of inflammation, apoptosis, and endothelial activation are associated with clinical outcomes in patients with bacteremia and sepsis regardless of microbial etiology.
Abstract readLetter
In one paragraph
Article in Virulence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- The value of lymphocyte-to-C-reactive protein ratio for predicting clinical outcomes in patients with sepsis in intensive care unit: a retrospective single-center study.Frontiers in molecular biosciences · 2024Article
- Elevated brain derived neurotrophic factor in plasma and interleukin-6 levels in cerebrospinal fluid in meningitis compared to cerebral malaria.Journal of the neurological sciences · 2023Article
- MICROVASCULAR ENDOTHELIAL ACTIVATION/DYSFUNCTION AND DYSREGULATION OF THE ANGIOPOIETIN-TIE2 SYSTEM IN THE PATHOGENESIS OF LIFE-THREATENING INFECTIONS.Transactions of the American Clinical and Climatological Association · 2023Article
- Biomarker combinations in predicting sepsis in hospitalized children with fever.BMC pediatrics · 2022Article
- Posterior Reversible Encephalopathy in Sepsis-Associated Encephalopathy: Experience from a Single Center.Neurocritical care · 2022Observational
- Colivelin, a synthetic derivative of humanin, ameliorates endothelial injury and glycocalyx shedding after sepsis in mice.Frontiers in immunology · 2022Article
- Comparison of host endothelial, epithelial and inflammatory response in ICU patients with and without COVID-19: a prospective observational cohort study.Critical care (London, England) · 2021Observational
- Fever in returning travellers and migrants: disease severity markers to improve triage and management.Journal of travel medicine · 2020Article
- sTREM-1 predicts mortality in hospitalized patients with infection in a tropical, middle-income country.BMC medicine · 2020Article
- Host-Based Prognostic Biomarkers to Improve Risk Stratification and Outcome of Febrile Children in Low- and Middle-Income Countries.Frontiers in pediatrics · 2020Article
- Endotoxemia-Induced Release of Pro-inflammatory Mediators Are Associated With Increased Glomerular Filtration Rate in HumansFrontiers in medicine · 2020Article
- Plasma concentrations of secretory leukocyte protease inhibitor (SLPI) differ depending on etiology and severity in community-onset bloodstream infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Article
- Higher Plasma Endothelial Markers in Adults with Cystic Fibrosis Compared with Healthy Age-matched Control Subjects.Annals of the American Thoracic Society · 2019Article
- Biomarkers of endothelial activation/dysfunction distinguish sub-groups of Ugandan patients with sepsis and differing mortality risks.JCI insight · 2019Observational
- Integrated fever management: disease severity markers to triage children with malaria and non-malarial febrile illness.Malaria journal · 2018Article
- Clinician-initiated research on treating the host response to pandemic influenza.Human vaccines & immunotherapeutics · 2018Article
- Endothelial Activation: The Ang/Tie Axis in Sepsis.Frontiers in immunology · 2018Review
- A Two-Biomarker Model Predicts Mortality in the Critically Ill with Sepsis.American journal of respiratory and critical care medicine · 2017Article
- Circulating levels of soluble Fas (sCD95) are associated with risk for development of a nonresolving acute kidney injury subphenotype.Critical care (London, England) · 2017Article
- Tie1: an orphan receptor provides context for angiopoietin-2/Tie2 signaling.The Journal of clinical investigation · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
William O Hahna Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington , Seattle , WA , USA.
Carmen Mikacenicb Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington , Seattle , WA , USA.
Brenda L Pricec Department of Biostatistics , University of Washington , Seattle , WA , USA.
Susanna Harju-Bakerb Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington , Seattle , WA , USA.
Ronit Katzd Kidney Research Institute, University of Washington , Seattle , WA , USA.
Jonathan Himmelfarbd Kidney Research Institute, University of Washington , Seattle , WA , USA.
Mark M Wurfelb Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington , Seattle , WA , USA.
W Conrad Lilesa Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington , Seattle , WA , USA.
Funding
HOST DEFENSE TRAINING IN ALLERGY AND INFECTIOUS DISEASEST32AI007044 · NIAID · UNIVERSITY OF WASHINGTON · PI DAVID Neal FREDRICKS · 1985 to 2026
$14.6MInfluence of TLR1 Polymorphisms on T-Regulatory Cells in ARDSK23HL120896 · NHLBI · UNIVERSITY OF WASHINGTON · PI MIKACENIC, CARMEN R · 2014 to 2018
$881kNHLBI NIH HHS K23 HL120896NIAID NIH HHS T32 AI007044
Abstract
PubMed holds no abstract for this paper.
Indexed as
ApoptosisAdultAgedBacteremiaBiomarkersCohort StudiesFemaleHumansMaleMiddle AgedProspective StudiesRetrospective StudiesSepsisBiomarkersangiopoietin-1angiopoietin-2bacteremiaG-CSFgram-negativegram-positiveIL-6IL-8sepsissFASsVAM-1TNFR-1
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.