Evidence map›Paper›PMID 26818005›Full record

ArticleThe Prostate2016

Trichomonas vaginalis infection and risk of advanced prostate cancer.

Irene M Shui, Suzanne Kolb, Christi Hanson, Siobhan Sutcliffe, Jennifer R Rider, Janet L Stanford

Open access · greenAbstract read
In one paragraph

Article in The Prostate, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. No Association ofCancers · 2023
    Article
  3. Infinity war:Microbial cell (Graz, Austria) · 2023
    Review
  4. Multiple pathogens and prostate cancer.Infectious agents and cancer · 2022
    Review
  5. Review
  6. Article
  7. Molecular Examination ofEthiopian journal of health sciences · 2021
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Irene M ShuiDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Suzanne KolbDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Christi HansonDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Siobhan SutcliffeDivision of Public Health Sciences and the Alvin J Siteman Cancer Center, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Jennifer R RiderDepartment of Epidemiology, Harvard TH Chan School of Public Health, Boston, Massachusetts.
Janet L StanfordDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Fred Hutch Cancer Center · USAlvin J. Siteman Cancer CenterBoston University · USUniversity of Washington · US

Funding

TRANSCRIPTOME AND PROTEOME STRATIFICATION OF PROSTATE ADENOCARCINOMA PHENOTYPESP50CA097186 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI John Kyung Lee · 2002 to 2026
$58.1M
NSAIDS and Other Medications in Prostate Cancer EtiologyR01CA092579 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI STANFORD, JANET L · 2001 to 2005
$3.2M
Aggressive Prostate Cancer: Linking Epigenomics and Genetics for PreventionK05CA175147 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI STANFORD, JANET L · 2014 to 2018
$445k
PROSTATE CANCER IN RELATION TO VASECTOMYR01CA056678 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI STANFORD, JANET L · 1993 to 1997
–
NCI NIH HHS K05 CA175147NCI NIH HHS P50 CA097186NCI NIH HHS R01 CA056678NCI NIH HHS R01 CA092579
6 · The paper itself

Abstract

backgroundThe epidemiologic evidence for an association of Trichomonas vaginalis (Tv) with overall prostate cancer is mixed, but some studies suggest Tv may increase risk of more aggressive disease. The aim of this study was to assess whether Tv serostatus is associated with advanced or fatal prostate cancer.

methodsA total of 146 men with advanced (metastatic or fatal) prostate cancer and 181 age-matched controls were selected from two prior population-based, case-control studies. Tv serostatus was determined with the same laboratory methods used in previous epidemiologic studies. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using multivariable logistic regression to compare Tv serostatus in prostate cancer cases and controls adjusted for potential confounders.

resultsThe seroprevalence of Tv in controls was 23%. Tv serostatus was not associated with an increased risk of metastatic or fatal prostate cancer (ORs < 1).

conclusionsOur study does not support an increased risk of advanced or fatal prostate cancer in men seropositive for Tv.

Indexed as

AgedHumansMaleMiddle AgedProstateProstatic NeoplasmsRisk FactorsSeverity of Illness IndexTrichomonas InfectionsTrichomonas vaginalisprostate cancersexually transmitted infectionsTrichomonas vaginalis

Identifiers

PMID26818005
PMCPMC5002353
OpenAlexW2255924832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.