Evidence map›Paper›PMID 26817901›Full record

ArticleMedicine2016

Asthma Is Associated With a Subsequent Risk of Peripheral Artery Disease: A Longitudinal Population-Based Study.

Chih-Wei Yao, Te-Chun Shen, Chiung-Ray Lu, Yu-Chiao Wang, Cheng-Li Lin, Chih-Yen Tu, Te-Chun Hsia, Chuen-Ming Shih, Wu-Huei Hsu, Fung-Chang Sung

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Strength of association between comorbidities and asthma: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023
    Pooled it
  2. Review
  3. Review
  4. Migraine as a Risk Factor for Peripheral Artery Occlusive Disease: A Population-Based Cohort Study.International journal of environmental research and public health · 2020
    Article
  5. Article
  6. Article
  7. Inhaled Corticosteroids in Asthma: Promoting or Protecting Against Atherosclerosis?Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Chih-Wei YaoFrom the Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital (C-WY, T-CS, C-YT, T-CH, C-MS, W-HH); Graduate Institute of Clinical Medicine Science, College of Medicine, China Medical University (T-CS, F-CS); Division of Cardiology, Department of Internal Medicine (C-RL); Management Office for Health Data, China Medical University Hospital (Y-CW, C-LL, F-CS); Department of Health Services Administration, College of Public Health, China Medical University, Taichung, Taiwan (F-CS).
Te-Chun Shen
Chiung-Ray Lu
Yu-Chiao Wang
Cheng-Li Lin
Chih-Yen Tu
Te-Chun Hsia
Chuen-Ming Shih
Wu-Huei Hsu
Fung-Chang Sung
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma has been associated with the atherosclerosis risk, but not clear of peripheral artery disease (PAD). We attempted to examine the risk of PAD in patients with asthma.From the insurance claims data of Taiwan, we identified 28,158 newly diagnosed asthma patients in 2000 to 2005 and 56,316 persons without asthma randomly selected into the comparison cohort, frequency matched by sex, age, and the date of diagnosis. Both cohorts were followed up until the end of 2011 to estimate the incident PAD. Adjusted hazard ratios (aHRs) of PAD were estimated using the Cox proportional hazards model after controlling for sex, age, and comorbidities.The incidence of PAD was 1.46 times higher in the asthma cohort than in the comparison cohort, with an aHR of 1.34 [95% confidence interval (CI) = 1.24-1.45]. Incidence of PAD was higher in men, the aged, and those with comorbidities in both cohorts. The aHRs of PAD remained significant for the asthma cohort in all subgroups of sex, age, and the presence of comorbidity. The aHRs of PAD were 14.1 (95% CI = 8.18-24.5) in asthma patients with multiple emergency visits and 22.3 (95% CI = 15.6-31.9) for those with multiple hospitalizations.Although smoking is a potential confounding factor, this study suggests patients with asthma have a significantly higher risk of developing PAD than the general population. The results also support the notion that poor control of asthma status is a key factor in subsequent PAD development.

Indexed as

AdultAgedAge FactorsAsthmaFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedPeripheral Arterial DiseaseProportional Hazards ModelsRisk FactorsSex FactorsTaiwanYoung Adult

Identifiers

PMID26817901
PMCPMC4998275
OpenAlexW2327675848

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.