Evidence map›Paper›PMID 26817870›Full record

ArticleMedicine2016

Association of Head and Neck Cancers in Chronic Osteomyelitis: A National Retrospective Cohort Study.

Chia-Ta Tsai, Mao-Wang Ho, Dana Lin, Hsuan-Ju Chen, Chih-Hsin Muo, Chun-Hung Tseng, Wen-Chi Su, Ming-Chia Lin, Chia-Hung Kao

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chia-Ta TsaiFrom the Division of Infectious Disease, Department of Internal Medicine, China Medical University Hospital (C-TT, M-WH); Graduate Institute of Clinical Medical Science and School of Medicine, College of Medicine, China Medical University (C-TT, W-CS, C-HK); Management Office for Health Data, China Medical University Hospital (DL, H-JC, C-HM); School of Medicine, China Medical University (H-JC, C-HM); Department of Neurology, China Medical University Hospital (C-HT); School of Medicine, China Medical University College of Medicine, Taichung (C-HT); Department of Nuclear Medicine, E-Da Hospital, I-Shou University, Kaohsiung (M-CL); and Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan (C-HK).
Mao-Wang Ho
Dana Lin
Hsuan-Ju Chen
Chih-Hsin Muo
Chun-Hung Tseng
Wen-Chi Su
Ming-Chia Lin
Chia-Hung Kao
China Medical University Hospital · TWChina Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of study is to determine whether chronic osteomyelitis (COM) is linked to an increased risk of head and neck cancer (HNC).We identify 17,033 patients with osteomyelitis and 68,125 subjects without osteomyelitis during 1996 to 2010 periods. Multivariable Cox proportional hazards regression analysis was used to measure the hazard ratio (HR) of head and neck cancer for the osteomyelitis cohort compared with the comparison cohort.A total of 99 patients in the COM and 228 patients in the comparison cohort developed HNC during an average 5.12 years of follow-up period. The incidence rate of HNC in the COM cohort was 1.51-fold (95% confidence interval [CI]: 1.17-1.95) higher than that in the comparison cohort after adjusting gender, age, urbanization level, monthly income, and comorbidities. In subgroup analysis, younger (less than 45 years-old) and patients without comorbidities have greater risks (adjusted HR: 2.29 [95% CI:1.43-3.66] and 1.74 [95% CI:1.28-2.38] respectively).This study results suggested the association between COM and HNC, particularly in younger population and patients without comorbidities.

Indexed as

AdultAgedChronic DiseaseCohort StudiesFemaleHead and Neck NeoplasmsHumansIncidenceMaleMiddle AgedOsteomyelitisProportional Hazards ModelsRegression AnalysisRetrospective StudiesRisk AssessmentRisk Factors

Identifiers

PMID26817870
PMCPMC4998244
OpenAlexW2327483113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.