Trial reportBMC complementary and alternative medicine2016
Effect of transcutaneous acupoint electrical stimulation on propofol sedation: an electroencephalogram analysis of patients undergoing pituitary adenomas resection.
Trial report in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Transcutaneous electrical acupoint stimulation for prevention of postoperative delirium in geriatric patients with silent lacunar infarction: a preliminary study.Clinical interventions in aging · 2018Trial
- Multistage acupuncture intervention perioperatively: a clinical optimization plan based on the ERAS concept.Frontiers in medicine · 2026Article
- Article
- Efficacy of preoperative transcutaneous electrical acupoint stimulation in reducing postoperative delirium in older adults undergoing orthopedic surgery: a randomized controlled trial.Frontiers in neurology · 2025Article
- Electroacupuncture Alters BCI-Based Brain Network in Stroke Patients.Computational intelligence and neuroscience · 2022Article
- EEG and ECG Power Spectrum Analysis of Sedative Effects on Propofol-Anesthetized Rats with Electroacupuncture.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Transcutaneous Electrical Acupoint Stimulation Improved Preoperative Blood Pressure in Gynecological Malignant Tumor Patients With Hypertension: A Randomized, Controlled Trial.Frontiers in oncology · 2022Article
- Multipoint transcutaneous electrical stimulation reduces median effective plasma concentration of propofol: A randomised clinical trial.Indian journal of anaesthesia · 2020Article
- Cough Suppression during Flexible Bronchoscopy Using Transcutaneous Electric Acupoint Stimulation: A Randomized Controlled Study.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Pain management of surgical abortion using transcutaneous acupoint electrical stimulation: An orthogonal prospective study.The journal of obstetrics and gynaecology research · 2018Article
- Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTranscutaneous acupoint electrical stimulation (TAES) as a needleless acupuncture has the same effect like traditional manual acupuncture. The combination of TAES and anesthesia has been proved valid in enhancing the anesthetic effects but its mechanisms are still not clear.
methodsIn this study, we investigated the effect of TAES on anesthesia with an electroencephalogram (EEG) oscillation analysis on surgery patients anesthetized with propofol, a widely-used anesthetic in clinical practice. EEG was continuously recorded during light and deep propofol sedation (target-controlled infusion set at 1.0 and 3.0 μg/mL) in ten surgery patients with pituitary tumor excision. Each concentration of propofol was maintained for 6 min and TAES was given at 2-4 min. The changes in EEG power spectrum at different frequency bands (delta, theta, alpha, beta, and gamma) and the coherence of different EEG channels were analyzed.
resultsOur result showed that, after TAES application, the EEG power increased at alpha and beta bands in light sedation of propofol, but reduced at delta and beta bands in deep propofol sedation (p < 0.001). In addition, the EEG oscillation analysis showed an enhancement of synchronization at low frequencies and a decline in synchronization at high frequencies between different EEG channels in either light or deep propofol sedation.
conclusionsOur study showed evidence suggested that TAES may have different effects on propofol under light and deep sedation. TAES could enhance the sedative effect of propofol at low concentration but reduce the sedative effect of propofol at high concentration.
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