Evidence map›Paper›PMID 26816606›Full record

Observational studyJournal of diabetes investigation2016

Efficacy and safety of insulin degludec in Japanese patients with type 1 and type 2 diabetes: 24-week results from the observational study in routine clinical practice.

Kazuhiro Kobuke, Masayasu Yoneda, Shuhei Nakanishi, Haruya Ohno, Shusaku Maeda, Genshi Egusa

Open access · goldAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of diabetes investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Glycemic Control in a Real-Life Setting in Patients with Type 2 Diabetes Treated with IDegLira at a Single Swiss Center.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2017
    Article
  7. Article
  8. Observational
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kazuhiro KobukeDepartment of Molecular and Internal Medicine Graduate School of Biomedical & Health Sciences Hiroshima University Hiroshima Japan.
Masayasu YonedaDepartment of Molecular and Internal Medicine Graduate School of Biomedical & Health Sciences Hiroshima University Hiroshima Japan.
Shuhei NakanishiDepartment of Metabolism and Endocrinology Hiroshima Red Cross Hospital & Atomic Bomb Survivors Hospital Hiroshima Japan.
Haruya OhnoDepartment of Molecular and Internal Medicine Graduate School of Biomedical & Health Sciences Hiroshima University Hiroshima Japan.
Shusaku MaedaDepartment of Molecular and Internal Medicine Graduate School of Biomedical & Health Sciences Hiroshima University Hiroshima Japan.
Genshi EgusaEgusa Genshi Clinic Hiroshima Japan.
Hiroshima University · JPHiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is first observational prospective study of insulin degludec in routine clinical practice that we evaluated the effect on glycemic control and risk of hypoglycemia in basal-bolus insulin therapy. We found that insulin degludec can maintain glycemic control at a lower insulin dose and frequency of hypoglycemia in type 1 diabetes, while it can improve glycemic control at equally insulin dose in type 2 diabetes. These results mean that insulin degludec is of use in routine clinical practice.

Indexed as

Asian PeopleAdultAgedBlood GlucoseDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleHumansInjections, SubcutaneousInsulin, Long-ActingJapanMaleMiddle AgedProspective StudiesTime FactorsTreatment OutcomeBlood Glucoseinsulin degludecInsulin, Long-ActingBasal–bolus treatmentHypoglycemiaInsulin degludec

Identifiers

PMID26816606
PMCPMC4718095
OpenAlexW1659695478

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.