Evidence map›Paper›PMID 26816602›Full record

SynthesisJournal of diabetes investigation2016

Higher intake of fruits, vegetables or their fiber reduces the risk of type 2 diabetes: A meta-analysis.

Ping-Yu Wang, Jun-Chao Fang, Zong-Hua Gao, Can Zhang, Shu-Yang Xie

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Journal of diabetes investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
165citing papers in PubMed, 15 pooled it
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

165 citing papers in PubMed, 15 syntheses or guidelines pooled it, 321 citations in OpenAlex.

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105 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ping-Yu WangDepartment of Biochemistry Binzhou Medical University YanTai ShanDong China.
Jun-Chao FangDepartment of Biochemistry Binzhou Medical University YanTai ShanDong China.
Zong-Hua GaoDepartment of Biochemistry Binzhou Medical University YanTai ShanDong China.
Can ZhangGenetics and Aging Research Unit MassGeneral Institute for Neurodegenerative Disease Department of Neurology Massachusetts General Hospital and Harvard Medical School Charlestown Massachusetts USA.
Shu-Yang XieDepartment of Biochemistry Binzhou Medical University YanTai ShanDong China.
Binzhou Medical University · CNBinzhou University · CNMaineGeneral Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionSome previous studies reported no significant association of consuming fruit or vegetables, or fruit and vegetables combined, with type 2 diabetes. Others reported that only a greater intake of green leafy vegetables reduced the risk of type 2 diabetes. To further investigate the relationship between them, we carried out a meta-analysis to estimate the independent effects of the intake of fruit, vegetables and fiber on the risk of type 2 diabetes. MATERIALS AND

methodsSearches of MEDLINE and EMBASE for reports of prospective cohort studies published from 1 January 1966 to 21 July 2014 were carried out, checking reference lists, hand-searching journals and contacting experts.

resultsThe primary analysis included a total of 23 (11 + 12) articles. The pooled maximum-adjusted relative risk of type 2 diabetes for the highest intake vs the lowest intake were 0.91 (95% confidence interval [CI] 0.87-0.96) for total fruits, 0.75 (95% CI 0.66-0.84) for blueberries, 0.87 (95% CI 0.81-0.93) for green leafy vegetables, 0.72 (95% CI 0.57-0.90) for yellow vegetables, 0.82 (95% CI 0.67-0.99) for cruciferous vegetables and 0.93 (95% CI 0.88-0.99) for fruit fiber in these high-quality studies in which scores were seven or greater, and 0.87 (95% CI 0.80-0.94) for vegetable fiber in studies with a follow-up period of 10 years or more.

conclusionsA higher intake of fruit, especially berries, and green leafy vegetables, yellow vegetables, cruciferous vegetables or their fiber is associated with a lower risk of type 2 diabetes.

Indexed as

FruitVegetablesDiabetes Mellitus, Type 2Dietary FiberHumansProspective StudiesRisk FactorsDietary FiberMeta‐analysisNutrition intakeType 2 diabetes

Identifiers

PMID26816602
PMCPMC4718092
OpenAlexW1558240244

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.