ReviewJournal of contemporary brachytherapy2015
Brachytherapy in non melanoma skin cancer of eyelid: a systematic review.
Review in Journal of contemporary brachytherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- The Safety of Radiotherapy in the Treatment of Primary Cutaneous B-Cell Lymphoma: A Multidisciplinary Systematic Review.Frontiers in oncology · 2020Pooled it
- Expert opinion: radiotherapy for basal cell carcinoma : Recommendations from the DEGRO Dermatooncology Working Group.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Considerations on HDR brachytherapy for eyelid carcinoma.Journal of contemporary brachytherapy · 2026Article
- High-dose-rate brachytherapy for eyelid carcinoma: Implant technique and review.Journal of contemporary brachytherapy · 2025Article
- The irreplaceable art of brachytherapy: A technical note on interstitial high-dose-rate interventional radiotherapy (brachytherapy) in eyelid tumors.Journal of contemporary brachytherapy · 2025Article
- Brachytherapy for eyelid cancers: Re-defining outcomes and esthetics in rare histologies.Journal of contemporary brachytherapy · 2025Article
- Protective eye device for eyelid brachytherapy: Technical report of an innovative personalized method.Annals of medicine and surgery (2012) · 2025Article
- Interstitial brachytherapy for periocular nonmelanoma skin cancers: Impact on organ and function preservation.Technical innovations & patient support in radiation oncology · 2024Article
- Implementing high-dose rate surface mould brachytherapy for carcinoma of eyelid: a practical approach and weekly review.Radiation oncology journal · 2024Article
- Treatment of Basal Cell Carcinoma of the Lower Eyelid With High-Dose-Rate Brachytherapy.Cureus · 2024Article
- Early clinical experience with a degraded 4 MeV electron beam in radiotherapy of superficial basal cell carcinoma.Physics and imaging in radiation oncology · 2023Article
- Lines under the eyes: a large prospective case series of linear basal cell carcinomas.Archives of dermatological research · 2023Article
- Impact of GBBS algorithm on post-mastectomy scar boost irradiation of breast using catheter flap.Journal of contemporary brachytherapy · 2021Article
- Interstitial HDR Brachytherapy in the Treatment of Non-Melanocytic Skin Cancers around the Eye.Cancers · 2021Article
- Computed tomography-based flap brachytherapy for non-melanoma skin cancers of the face.Journal of contemporary brachytherapy · 2021Article
- Artificial intelligence (AI) and interventional radiotherapy (brachytherapy): state of art and future perspectives.Journal of contemporary brachytherapy · 2020Review
- Can brachytherapy be properly considered in the clinical practice? Trilogy project: The vision of the AIRO (Italian Association of Radiotherapy and Clinical Oncology) Interventional Radiotherapy study group.Journal of contemporary brachytherapy · 2020Article
- A dosimetric study of electron beam therapy vs. high-dose-rate mould brachytherapy in adjuvant treatment of non-melanoma skin carcinomas of the head and neck region.Journal of contemporary brachytherapy · 2019Article
- Mould-based surface high-dose-rate brachytherapy for eyelid carcinoma.Journal of contemporary brachytherapy · 2019Article
- Current state of interventional radiotherapy (brachytherapy) education in Italy: results of the INTERACTS survey.Journal of contemporary brachytherapy · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeNon melanoma skin cancers (NMSC) of eyelid are uncommon. Many treatments approach are available with surgery being considered as the gold standard. Radiotherapy is an effective alternative in patients unfit for surgery. Brachytherapy (BT) might be a better therapeutic option due high radiation dose concentration to the tumor and rapid dose fall-off resulting in normal tissues sparing. The aim of this review is to evaluate local control, toxicity, and functional cosmetic outcome of BT in NMSC of eyelid. MATERIAL AND
methodsA systematic search of the bibliographic databases PubMed, Scopus, and Cochrane Library from the earliest possible date through October 2015 was performed. Only studies published in English were included.
resultsSix articles fulfilled the selection criteria and were included in our review. Due to high risk of bias, all studies were classified to provide a low level of evidence (according to Scottish Intercollegiate Guidelines Network Classification). No randomized controlled trials or case control studies were founded. Brachytherapy was well tolerated with acceptable toxicity and high local control rates (median: 95.2%). Functional and cosmetic outcome were reported in five study as acceptable good functional-cosmetic outcome (median: 100%).
conclusionsTo date, few evidences are available on the role of BT in eyelid NMSC, and they show satisfactory results in terms of local control and functional cosmetic outcome. Therefore, prospective controlled trials are justified.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.