ArticleScience (New York, N.Y.)2016
Neural circuits. Inhibition protects acquired song segments during vocal learning in zebra finches.
Article in Science (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
78 citing papers in PubMed, 147 citations in OpenAlex.
- Dopamine D2 Receptor Modulates Exercise Related Effect on Cortical Excitation/Inhibition and Motor Skill Acquisition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Trial
- Excitation-inhibition imbalance underlies perioperative neurocognitive disorders: a single-nucleus transcriptomic perspective in mice hippocampus.Molecular psychiatry · 2026Article
- Vocal and social impairments in songbirds embryonically exposed to an autism risk factor.iScience · 2026Article
- Nightly changes in neural activity and auditory processing of song control neurons depend on melatonin.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Article
- Social familiarity strengthens neural and vocal responses to conspecific calls in zebra finches.PLoS computational biology · 2026Article
- Article
- Correctness is its own reward: bootstrapping error signals in self-guided reinforcement learning.bioRxiv : the preprint server for biology · 2025Article
- Article
- Differential behavioral engagement of inhibitory interneuron subtypes in the zebra finch brain.Neuron · 2025Article
- Perineuronal nets in motor circuitry regulate the performance of learned vocalizations in songbirds.Communications biology · 2025Article
- Variable and slow-paced neural dynamics in HVC underlie plastic song production in juvenile zebra finches.BMC neuroscience · 2024Article
- Millisecond-scale motor coding precedes sensorimotor learning in songbirds.bioRxiv : the preprint server for biology · 2024Article
- Female calls promote song learning in male juvenile zebra finches.Nature communications · 2024Article
- Disinhibition enables vocal repertoire expansion after a critical period.Nature communications · 2024Article
- Resilience of A Learned Motor Behavior After Chronic Disruption of Inhibitory Circuits.bioRxiv : the preprint server for biology · 2024Article
- Independent inhibitory control mechanisms for aggressive motivation and action.Nature neuroscience · 2024Article
- A novel paradigm for observational learning in rats.Cognitive neurodynamics · 2024Article
- Hemispheric dominance in HVC is experience-dependent in juvenile male zebra finches.Scientific reports · 2024Article
- Tutor auditory memory for guiding sensorimotor learning in birdsong.Frontiers in neural circuits · 2024Review
- Daily vocal exercise is necessary for peak performance singing in a songbird.Nature communications · 2023Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Vocal imitation involves incorporating instructive auditory information into relevant motor circuits through processes that are poorly understood. In zebra finches, we found that exposure to a tutor's song drives spiking activity within premotor neurons in the juvenile, whereas inhibition suppresses such responses upon learning in adulthood. We measured inhibitory currents evoked by the tutor song throughout development while simultaneously quantifying each bird's learning trajectory. Surprisingly, we found that the maturation of synaptic inhibition onto premotor neurons is correlated with learning but not age. We used synthetic tutoring to demonstrate that inhibition is selective for specific song elements that have already been learned and not those still in refinement. Our results suggest that structured inhibition plays a crucial role during song acquisition, enabling a piece-by-piece mastery of complex tasks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.