ArticleEuropean journal of nutrition2016
Intake of fish and long-chain omega-3 polyunsaturated fatty acids and incidence of metabolic syndrome among American young adults: a 25-year follow-up study.
Article in European journal of nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Food Groups and Risk of Overweight, Obesity, and Weight Gain: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies.Advances in nutrition (Bethesda, Md.) · 2019Pooled it
- Pooled it
- Trial
- Evaluating Changes in Omega-3 Fatty Acid Intake after Receiving Personal FADS1 Genetic Information: A Randomized Nutrigenetic Intervention.Nutrients · 2017Trial
- Article
- Global burden of ischemic heart disease due to omega-3 deficiency: 204-country analysis, 1990-2021.Frontiers in nutrition · 2025Article
- Dietary patterns derived by reduced rank regression are associated with lipid disorders among Korean adults: a cross-sectional analysis.Lipids in health and disease · 2024Article
- Dietary fatty acid patterns and risk of metabolic syndrome: Tehran lipid and glucose study.European journal of medical research · 2023Article
- Effects of Omega-3 Fatty Acids Supplementation on Serum Lipid Profile and Blood Pressure in Patients with Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Foods (Basel, Switzerland) · 2023Review
- Associations between Timing and Duration of Eating and Glucose Metabolism: A Nationally Representative Study in the U.S.Nutrients · 2023Article
- New Advances in Metabolic Syndrome, from Prevention to Treatment: The Role of Diet and Food.Nutrients · 2023Review
- Meat consumption and the risk of general and central obesity: the Shahedieh study.BMC research notes · 2022Article
- MicroRNA-193a-5p Regulates the Synthesis of Polyunsaturated Fatty Acids by Targeting Fatty Acid Desaturase 1 (Biomolecules · 2021Article
- Fish Consumption: A Review of Its Effects on Metabolic and Hormonal Health.Nutrition and metabolic insights · 2021Review
- Targeting Cardiovascular Risk Factors Through Dietary Adaptations and Caloric Restriction Mimetics.Frontiers in nutrition · 2021Review
- Intake of Animal Source Foods in Relation to Risk of Metabolic Syndrome.Preventive nutrition and food science · 2020Article
- The association of fish consumption and its urinary metabolites with cardiovascular risk factors: the International Study of Macro-/Micronutrients and Blood Pressure (INTERMAP).The American journal of clinical nutrition · 2020Article
- Menopause-Associated Lipid Metabolic Disorders and Foods Beneficial for Postmenopausal Women.Nutrients · 2020Review
- Seafood intake and the development of obesity, insulin resistance and type 2 diabetes.Nutrition research reviews · 2019Review
- Nutrients in Fish and Possible Associations with Cardiovascular Disease Risk Factors in Metabolic Syndrome.Nutrients · 2018Review
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
Abstract
purposeStudies suggest that long-chain ω-3 polyunsaturated fatty acid (LCω3PUFA) intake and its primary food source-fish-may have beneficial effects on the individual components of metabolic syndrome (MetS). We examined the longitudinal association between fish or LCω3PUFA intake and MetS incidence.
methodsWe prospectively followed 4356 American young adults, free from MetS and diabetes at baseline, for incident MetS and its components in relation to fish and LCω3PUFA intake. MetS was defined by the National Cholesterol Education Program/Adult Treatment Panel III criteria. Cox proportional hazards model was used for analyses, controlling for socio-demographic, behavioral, and dietary factors.
resultsDuring the 25-year follow-up, a total of 1069 incident cases of MetS were identified. LCω3PUFA intake was inversely associated with the incidence of MetS in a dose-response manner. The multivariable adjusted hazards ratio (HR) [95 % confidence interval (CI)] of incident MetS was 0.54 (95 % CI 0.44, 0.67; P for linear trend < 0.01) as compared the highest to the lowest quintile of LCω3PUFA intake. A threshold inverse association was found between non-fried fish consumption and the incidence of MetS. The multivariable adjusted HRs (95 % CIs) from the lowest to the highest quintile were 1.00, 0.70 (0.51, 0.95), 0.68 (0.52, 0.91), 0.67 (0.53, 0.86), and 0.71 (0.56, 0.89) (P for linear trend = 0.49). The observed inverse associations were independent of the status of baseline individual components of MetS.
conclusionsOur findings suggest that intakes of LCω3PUFAs and non-fried fish in young adulthood are inversely associated with the incidence of MetS later in life.
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Registered trials
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