ReviewThe New England journal of medicine2016
Neurobiologic Advances from the Brain Disease Model of Addiction.
Review in The New England journal of medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03831971 (The Influence of ANS-6637 on Midazolam Pharmacokinetics in Healthy Volunteers), which is not on this map. Cited by 701 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Influence of ANS-6637 on Midazolam Pharmacokinetics in Healthy Volunteers (SEARCH PK)
Who cites it
701 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Pharmacological and non-pharmacological modulation of striatal dopamine release: a meta-analysis of [Molecular psychiatry · 2026Pooled it
- Effect of addiction on brain glucose metabolism assessed by PET/CT molecular imaging: a systematic review and meta-analysis.Brain imaging and behavior · 2026Pooled it
- Comparative effects of different types of exercise interventions on addictive craving, negative affect, and cognitive function in substance use disorder: a substance-subgroup stratified network meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Alexithymia in neurodevelopmental populations: a scoping review of Down syndrome, autism spectrum disorder, and dual diagnosis.Frontiers in psychology · 2026Pooled it
- Prevalence of Dropout and Influencing Factors in Digital Psychosocial Intervention Trials for Adult Illicit Substance Users: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Common neural patterns of substance use disorder: a seed-based resting-state functional connectivity meta-analysis.Translational psychiatry · 2025Pooled it
- Problematic Gaming and Gambling: A Systematic Review of Task-Specific EEG Protocols.Journal of gambling studies · 2024Pooled it
- Neuroimaging of the effects of drug exposure or self-administration in rodents: A systematic review.Neuroscience and biobehavioral reviews · 2024Pooled it
- An opioid-withholding human laboratory paradigm during opioid agonist treatment for opioid use disorder and chronic pain: Phase- and dose-dependent effects of cannabidiol.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Trial
- Engagement in alcohol-free activities, community-level economic disadvantage, and heavy drinking following alcohol treatment.Journal of the experimental analysis of behavior · 2026Trial
- The Role of Melatonin in Smoking Cessation and COPD Management: A Randomized Controlled Trial.Canadian respiratory journal · 2026Trial
- Cannabidiol attenuates precuneus activation during appetitive cue exposure in individuals with alcohol use disorder.European archives of psychiatry and clinical neuroscience · 2025Trial
- The Effect of Digital Addiction Training on University Students' Digital Addiction, Sleep Quality, and Orexin-A Levels: Randomized Controlled Trial.BMC psychology · 2025Trial
- Positive Emotion Dysregulation in Opioid Use Disorder and Normalization by Mindfulness-Oriented Recovery Enhancement: A Secondary Analysis of a Randomized Clinical Trial.JAMA psychiatry · 2025Trial
- Across the spectrum: Acute alcohol responses in young adults with mild, moderate, and severe alcohol use disorder.Drug and alcohol dependence · 2025Trial
- Blood phosphatidylethanol measurements indicate GLP-1 receptor stimulation causes delayed decreases in alcohol consumption.Alcohol, clinical & experimental research · 2025Trial
- Preliminary effects of oral ANS-6637, an ALDH2 inhibitor, on cue-induced craving, safety and alcohol consumption among adults with alcohol use disorder: a proof-of-concept, randomized, human laboratory trial.Alcohol and alcoholism (Oxford, Oxfordshire) · 2025Trial
- Improvement in coping skills from culturally-adapted digital CBT for Spanish-speaking Hispanics with substance use disorder: Secondary analysis of a randomized clinical trial.Journal of substance use and addiction treatment · 2025Trial
- Dysregulated eating behaviour and microbiota-based interventions targeting eating disorders and food addiction.Gut microbes · 2026Review
- GutGut microbes · 2026Article
641 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.