ArticleEuropean journal of clinical pharmacology2016
Treatment of nausea and vomiting during pregnancy -a cross-sectional study among 712 Norwegian women.
Article in European journal of clinical pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06055192 (Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland: Survey Purity 2022
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Use of metoclopramide in the first trimester and risk of major congenital malformations: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Efficacy and Safety of Oral Meclizine for Growth Promotion in Children with Achondroplasia: A Phase 2 Clinical Trial.Calcified tissue international · 2025Trial
- Prevalence and Burden of Nausea and Vomiting in Pregnant Women: Final Analysis of the PURITY Survey.Journal of clinical medicine · 2026Article
- Prevalence and Associated Factors in Nausea and Vomiting Among Pregnant Women in Eastern Ethiopia: A Community-Based Cross-Sectional Study.Health services insights · 2026Article
- Article
- Phase 1b study on the repurposing of meclizine hydrochloride for children with achondroplasia.PloS one · 2023Article
- Patterns of antiemetic medication use during pregnancy: A multi-country retrospective cohort study.PloS one · 2022Article
- Antiemetic Prescription Fills in Pregnancy: A Drug Utilization Study Among 762,437 Pregnancies in Norway.Clinical epidemiology · 2021Article
- Use of drugs for gastrointestinal disorders: evidence from National Survey on Access, Use and Promotion of Rational Use of Medicines.Einstein (Sao Paulo, Brazil) · 2020Article
- The association between the degree of nausea in pregnancy and subsequent posttraumatic stress.Archives of women's mental health · 2019Article
- Reported time to onset of neurological adverse drug reactions among different age and gender groups using metoclopramide: an analysis of the global database Vigibase®.European journal of clinical pharmacology · 2018Article
- The effect of small group teaching on quality of life in pregnant women with nausea and vomiting: A clinical trial.Journal of education and health promotion · 2018Article
- Hyperemesis gravidarum and the risk of emotional distress during and after pregnancy.Archives of women's mental health · 2017Article
- History of depression and risk of hyperemesis gravidarum: a population-based cohort study.Archives of women's mental health · 2017Article
- The burden of nausea and vomiting during pregnancy: severe impacts on quality of life, daily life functioning and willingness to become pregnant again - results from a cross-sectional study.BMC pregnancy and childbirth · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purposes of this study were to investigate the treatments used for nausea and vomiting of pregnancy (NVP) according to NVP severity among Norwegian women and to assess whether maternal characteristics and attitudes were related to the use of pharmacological treatment of NVP.
methodsThis is a cross-sectional Web-based study. Pregnant women and mothers with children ≤1 year of age were eligible to participate. Data were collected through an anonymous online questionnaire accessible from November 10th, 2014 to January 31st, 2015.
resultsIn total, 712 women were included in the study, of which 62 (8.7 %), 439 (61.7 %) and 210 (29.5 %) had mild, moderate and severe NVP, respectively, according to the Pregnancy-Unique Quantification of Emesis (PUQE) classification. A total of 277 (38.9 %) women had used one or more antiemetics, of which meclizine, closely followed by metoclopramide, was the most commonly used. Different drug utilisation patterns were found between the groups of women with mild, moderate and severe NVP. Many with moderate or severe symptoms did not use any pharmacological treatment (70.2 and 32.9 %, respectively). Sick leave was given without initiating medical treatment in 266 (62.1 %) women. The women's beliefs about medicines had an important impact on their use of medicines for NVP.
conclusionsA large proportion of women suffered from moderate to severe symptoms of NVP, many of whom did not receive any pharmacological treatment. Many women, who had been on sick leave due to NVP, were not prescribed medicines.
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Registered trials
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